TY  - BOOK
AU  - Banda, Deliya R
AU  - Libin, Alexander V
AU  - Swain, Sandra M
AU  - Wang, Hong
TI  - A pilot study of a culturally targeted video intervention to increase participation of African American patients in cancer clinical trials
SN  - 1083-7159
PY  - 2012///
KW  - *African Americans/px [Psychology]
KW  - *Clinical Trials as Topic/mt [Methods]
KW  - *Neoplasms/eh [Ethnology]
KW  - *Patient Education as Topic/mt [Methods]
KW  - *Videotape Recording/mt [Methods]
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Neoplasms/th [Therapy]
KW  - Pilot Projects
KW  - Questionnaires
KW  - Research Design
KW  - MedStar Health Research Institute
KW  - MedStar National Rehabilitation Network
KW  - Washington Cancer Institute
KW  - Journal Article
KW  - Research Support, N.I.H., Extramural
N1  - Available online from MWHC library: 1996 - present
N2  - CONCLUSION: These data suggest utility of our video for increasing African American participation in clinical trials; PATIENTS AND METHODS: The primary study outcome was self-reported likelihood to participate in a therapeutic trial. Using a mixed methods approach, we developed the Attitudes and Intention to Enroll in Therapeutic Clinical Trials (AIET) instrument, a 30-item questionnaire measuring six attitudinal barriers to African American trial participation. We enrolled 108 eligible active treatment patients at a large urban cancer institute. McNemar's test for matched pairs was used to assess changes in attitudes and likelihood to enroll in a clinical trial at baseline and immediately after the video. Pre- and post-video AIET summative scores were analyzed by paired t-test for each attitudinal barrier; PURPOSE: Barriers to clinical trial participation among African American cancer patients are well characterized in the literature. Attitudinal barriers encompassing fear, distrust, and concerns about ethical misconduct are also well documented. To increase trial accrual, these attitudes must be adequately addressed, yet there remains a lack of targeted interventions toward this end. We developed a 15-minute culturally targeted video designed to impact six specific attitudes of African American cancer patients toward therapeutic trials. We conducted a pilot study to test in the first such intervention to increase intention to enroll; RESULTS: Patients' likelihood of enrolling in a clinical trial significantly increased post-video with 36% of the sample showing positive changes in intention [McNemar's (2) = 33.39, p < .001]. Paired t-tests showed significant changes in all six attitudinal barriers measured via AIET summative scores from pre- to post-video
UR  - http://dx.doi.org/10.1634/theoncologist.2011-0454
ER  -