TY  - BOOK
AU  - Barac, Ana
TI  - A review of genetics, arterial stiffness, and blood pressure in African Americans. [Review]
PY  - 2012///
KW  - *African Americans/ge [Genetics]
KW  - *Arteries/pa [Pathology]
KW  - *Blood Pressure/ge [Genetics]
KW  - *Hypertension/ge [Genetics]
KW  - Arteries/pp [Physiopathology]
KW  - Compliance
KW  - Genetic Predisposition to Disease
KW  - Heredity
KW  - Humans
KW  - Hypertension/eh [Ethnology]
KW  - Hypertension/pa [Pathology]
KW  - Hypertension/pp [Physiopathology]
KW  - Phenotype
KW  - Prevalence
KW  - Risk Assessment
KW  - Risk Factors
KW  - United States/ep [Epidemiology]
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
KW  - Review
N2  - The prevalence of hypertension in African Americans in the USA is among the highest in the world and increasing. The identification of genes and pathways regulating blood pressure in African Americans has been challenging. An early predictor of hypertension is arterial stiffness. The prevalence of arterial stiffness is significantly higher in African Americans compared to Caucasians. Approximately 20 % of the variance in arterial stiffness is estimated to be heritable. Identifying genes and biological pathways regulating arterial stiffness may provide insight into the genetics underlying the increased risk of hypertension in African Americans. This paper reviews the genetic findings to date in the area of arterial stiffness and blood pressure in African Americans with an emphasis on the current limitations and new efforts to move the field forward
UR  - http://dx.doi.org/10.1007/s12265-012-9362-y
ER  -