TY - BOOK AU - Barbash, Israel M AU - Ben-Dor, Itsik AU - Dvir, Danny AU - Lindsay, Joseph AU - Maluenda, Gabriel AU - Okubagzi, Petros AU - Pichard, Augusto D AU - Satler, Lowell F AU - Torguson, Rebecca AU - Waksman, Ron TI - Balloon aortic valvuloplasty for severe aortic stenosis as a bridge to transcatheter/surgical aortic valve replacement SN - 1522-1946 PY - 2013/// KW - *Aortic Valve Stenosis/th [Therapy] KW - *Balloon Valvuloplasty KW - *Cardiac Catheterization KW - *Heart Valve Prosthesis Implantation/mt [Methods] KW - Aged KW - Aged, 80 and over KW - Aortic Valve Stenosis/di [Diagnosis] KW - Aortic Valve Stenosis/mo [Mortality] KW - Aortic Valve Stenosis/pp [Physiopathology] KW - Aortic Valve Stenosis/su [Surgery] KW - Balloon Valvuloplasty/ae [Adverse Effects] KW - Balloon Valvuloplasty/mo [Mortality] KW - Cardiac Catheterization/ct [Contraindications] KW - Female KW - Heart Valve Prosthesis Implantation/ct [Contraindications] KW - Hemodynamics KW - Humans KW - Male KW - Patient Selection KW - Retrospective Studies KW - Risk Factors KW - Severity of Illness Index KW - Time Factors KW - Treatment Outcome KW - MedStar Heart & Vascular Institute KW - Comparative Study KW - Journal Article N1 - Available online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006 N2 - BACKGROUND: The introduction of transcatheter aortic valve replacement (TAVR) has led to a revival in BAV as treatment for patients with severe aortic stenosis; CONCLUSION: In high-risk patients with aortic stenosis and temporary contraindications to SAVR/TAVR, BAV may be used as a bridge to intervention with good mid-term outcomes. Copyright 2012 Wiley Periodicals, Inc; METHODS: A cohort of 472 patients underwent 538 BAV procedures. The cohort was divided into two groups: BAV alone 387 (81.9%) and BAV as a bridge 85 (18.1%) to (n = 65, TAVR; n = 20, surgery). Clinical, hemodynamic, and follow-up mortality data were collected; OBJECTIVES: This study aimed to determine success- and complication rates after balloon aortic valvuloplasty (BAV) and the outcome of BAV as a standalone therapy versus BAV as a bridge to transcatheter/surgical aortic valve replacement (T/SAVR); RESULTS: There was no significant difference between the two groups in mean age (81.7 + 8.3 vs. 83.2 + 10.9 years, P = 0.18), society of thoracic surgeons score (13.1 + 6.2 and 12.4 + 6.4, P = 0.4), logistic EuroSCORE (45.4 + 22.3 vs. 46.9 + 21.8, P = 0.43), and other comorbidities. The mean increase in aortic valve area was 0.39 + 0.25 in the BAV alone group and 0.42 + 0.26 in the BAV as a bridge group, P = 0.33. The decrease in mean gradient was 24.1 + 13.1 in the BAV alone group vs. 27.1 + 13.8 in the BAV as a bridge group, P = 0.06. During a median follow up of 183 days [54-409], the mortality rate was 55.2% (n = 214) in the BAV alone group vs. 22.3% (n = 19) in the BAV as a bridge group during a median follow-up of 378 days [177-690], P < 0.001 UR - http://dx.doi.org/10.1002/ccd.24682 ER -