TY - BOOK AU - Chan, Chee Man AU - Shorr, Andrew F AU - Woods, Christian J TI - Comparing the pulmonary embolism severity index and the prognosis in pulmonary embolism scores as risk stratification tools SN - 1553-5592 PY - 2012/// KW - *Pulmonary Embolism/di [Diagnosis] KW - *Pulmonary Embolism/mo [Mortality] KW - *Severity of Illness Index KW - Adult KW - Aged KW - Cohort Studies KW - Female KW - Humans KW - Male KW - Middle Aged KW - Predictive Value of Tests KW - Prognosis KW - Retrospective Studies KW - Risk Factors KW - MedStar Washington Hospital Center KW - Medicine/Pulmonary-Critical Care KW - Comparative Study KW - Journal Article KW - Observational Study N1 - Available in print through MWHC library: 2007 only N2 - BACKGROUND: Multiple risk stratification scoring systems exist to forecast outcomes in patients with acute pulmonary embolism (PE); CONCLUSIONS: The PREP score performed comparably to the PESI score for identifying PE patients at low risk for short-term and intermediate-term mortality.Copyright � 2011 Society of Hospital Medicine; DESIGN: Retrospective observational cohort study; INTERVENTION: The PESI and PREP scores were calculated; MEASUREMENTS: Raw PESI scores were segregated into risk class (I-V) and then dichotomized into low (I-II) versus high (III-V) risk groups; the raw PREP scores were divided into low (0-7) versus high (>7) risk groups. The primary endpoint was 30-day and 90-day mortality. We determined the negative predictive value and computed the area under the receiver operating characteristics (AUROC) curves to compare the ability of these scoring tools; OBJECTIVE: We evaluated the comparative validity of the PE severity index (PESI) and the prognosis in pulmonary embolism (PREP) scores to predict mortality in acute PE; PATIENTS: Consecutive adults (aged >18 years) diagnosed with acute PE; RESULTS: The cohort consisted of 302 subjects. Thirty-day mortality was 3.0%, and 4.0% died within 90 days. The PESI and the PREP performed similarly (PESI AUROC: 0.858 [95% confidence interval (CI), 0.773-0.943] vs 0.719 [95% CI, 0.563-0.875] for PREP). Segregating these scores into risk categories did not affect their discriminatory power (AUROC: 0.684 [95% CI, 0.559-0.810] for PESI and 0.790 [95% CI, 0.679-0.903] for PREP). The negative predictive value for death of being classified as low risk by the PESI or PREP was 100% and 99%, respectively; SETTING: Washington Hospital Center, Washington, DC UR - http://dx.doi.org/10.1002/jhm.932 ER -