TY  - BOOK
AU  - Catlett, Joseph
AU  - Lynce, Filipa
AU  - Malkovska, Vera
AU  - Pehlivanova, Marieta
TI  - Obesity in adult lymphoma survivors
SN  - 1026-8022
KW  - *Lymphoma/pp [Physiopathology]
KW  - *Obesity/pp [Physiopathology]
KW  - *Survivors
KW  - *Weight Gain/ph [Physiology]
KW  - Adult
KW  - Age Factors
KW  - Aged
KW  - Aged, 80 and over
KW  - Body Mass Index
KW  - Body Weight/de [Drug Effects]
KW  - Body Weight/ph [Physiology]
KW  - Body Weight/re [Radiation Effects]
KW  - Chemoradiotherapy
KW  - Female
KW  - Humans
KW  - Logistic Models
KW  - Lymphoma/dt [Drug Therapy]
KW  - Lymphoma/rt [Radiotherapy]
KW  - Male
KW  - Middle Aged
KW  - Retrospective Studies
KW  - Risk Factors
KW  - Sex Factors
KW  - Time Factors
KW  - Weight Gain/de [Drug Effects]
KW  - Weight Gain/re [Radiation Effects]
KW  - Young Adult
KW  - MedStar Health Research Institute
KW  - Washington Cancer Institute
KW  - Journal Article
N2  - As a result of therapeutic advances, survivors of lymphoma are now living longer. However, their mortality is higher when compared to the general population, probably due to multiple factors. Survivors of childhood leukemia and lymphoma appear to have an increased prevalence of obesity. The objectives of this retrospective study were to analyze weight 130912 after lymphoma treatment in an adult population and determine factors predictive of weight gain. Data were collected from 219 patients and analyzed sequentially at the initial visit and at 6, 12 and 18 months. There was a progressive increase in weight from the initial visit to 6 months (1.5% increase of initial body weight), 12 months (4.5%) and 18 months (6.4%). More than 9% of patients experienced weight gain greater than 20% during follow-up. There was a statistically significant association between the percentage of increase in weight and age, B symptoms and body mass index (BMI) at presentation. Younger patients, those with B symptoms or those with lower BMI manifested more weight gain (p = 0.0008, p = 0.0440 and p = 0.0009, respectively). Other assessed factors had no effect on weight gain including sex, race, lymphoma histology, disease outcome, radiation therapy, number of treatment regimens and use of steroids. Further studies are needed to explore long-term weight trends and their impact on the health of lymphoma survivors
UR  - http://dx.doi.org/10.3109/10428194.2011.619606
ER  -