TY  - BOOK
AU  - Pradka, Sarah P
AU  - Ricotta, John J
AU  - Trankiem, Christine T
TI  - Pylephlebitis and acute mesenteric ischemia in a young man with inherited thrombophilia and suspected foodborne illness
SN  - 0741-5214
KW  - *Colitis/et [Etiology]
KW  - *Foodborne Diseases/co [Complications]
KW  - *Ischemia/et [Etiology]
KW  - *Portal Vein
KW  - *Thrombophilia/co [Complications]
KW  - *Thrombophlebitis/et [Etiology]
KW  - *Vascular Diseases/et [Etiology]
KW  - Adult
KW  - Anti-Bacterial Agents/tu [Therapeutic Use]
KW  - Anticoagulants/tu [Therapeutic Use]
KW  - Colectomy
KW  - Colitis/di [Diagnosis]
KW  - Colitis/th [Therapy]
KW  - Colonoscopy
KW  - DNA Mutational Analysis
KW  - Factor V/ge [Genetics]
KW  - Foodborne Diseases/di [Diagnosis]
KW  - Foodborne Diseases/th [Therapy]
KW  - Heterozygote
KW  - Humans
KW  - Ischemia/di [Diagnosis]
KW  - Ischemia/th [Therapy]
KW  - Male
KW  - Mutation
KW  - Prothrombin/ge [Genetics]
KW  - Thrombolytic Therapy
KW  - Thrombophilia/di [Diagnosis]
KW  - Thrombophilia/ge [Genetics]
KW  - Thrombophilia/th [Therapy]
KW  - Thrombophlebitis/di [Diagnosis]
KW  - Thrombophlebitis/th [Therapy]
KW  - Tomography, X-Ray Computed
KW  - Treatment Outcome
KW  - Vascular Diseases/di [Diagnosis]
KW  - Vascular Diseases/th [Therapy]
KW  - MedStar Washington Hospital Center
KW  - Surgery/Trauma Surgery
KW  - Surgery/Vascular Surgery
KW  - Case Reports
KW  - Journal Article
N1  - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
N2  - We report on a young man who developed complicated pylephlebitis after foodborne illness. Despite antibiotics and resection of the focus of infectious colitis, he developed extensive small bowel infarction. He was treated with anticoagulation, local thrombolytic infusion, and resection of irreversibly ischemic small bowel. Thrombophilia workup demonstrated heterozygosity for factor V Leiden and the prothrombin G20210A mutation. The complications of pylephlebitis can be minimized by using systemic anticoagulation, thrombectomy, and/or local thrombolytic infusion along with antibiotics and surgical management of the infection. Evaluation for thrombophilic states should be considered, particularly if a patient does not respond to initial therapy. Copyright  2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved
UR  - http://dx.doi.org/10.1016/j.jvs.2011.12.055
ER  -