TY - BOOK AU - Giladi, Aviram M AU - Mete, Mihriye AU - Sanghavi, Kavya K AU - Shetty, Pragna N TI - Prescription Opioids and Patient-Reported Outcomes and Satisfaction After Carpal Tunnel Release Surgery PY - 2023/// KW - *Carpal Tunnel Syndrome KW - *Opioid-Related Disorders KW - Adult KW - Analgesics, Opioid/tu [Therapeutic Use] KW - Carpal Tunnel Syndrome/dt [Drug Therapy] KW - Carpal Tunnel Syndrome/su [Surgery] KW - Cohort Studies KW - Humans KW - Opioid-Related Disorders/dt [Drug Therapy] KW - Pain, Postoperative/dt [Drug Therapy] KW - Patient Reported Outcome Measures KW - Patient Satisfaction KW - Personal Satisfaction KW - Prescriptions KW - Prospective Studies KW - Curtis National Hand Center KW - MedStar Health Research Institute KW - Journal Article N2 - BACKGROUND: Amount of opioid use correlates poorly with procedure-related pain; however, prescription limits raise concerns about inadequate pain control and impacts on patient-reported quality indicators. There remain no consistent guidelines for postoperative pain management after carpal tunnel release (CTR). We sought to understand how postoperative opioid use impacts patient-reported outcomes after CTR; CONCLUSIONS: Patients remaining on a prescription after CTR reported worse outcomes compared to those who discontinued. Unexpectedly, the widest bMHQ score gap was seen across patients reporting lowest pain scores. Further research into this high-risk subgroup is needed to guide policy around using pain and patient-reported outcomes as quality measures. Level of Evidence: Level III; METHODS: This is a pragmatic cohort study using prospectively collected data from all adult patients undergoing uncomplicated primary CTR over 17 months at our center. Patients were categorized as having received or not received a postoperative opioid prescription, and then as remaining on a prescription opioid at 2-week follow-up or not. Questionnaires were completed before surgery and at 2-week follow-up. We collected brief Michigan Hand questionnaire (bMHQ) score, Patient-Reported Outcomes Measurement Information System Global Health score, satisfaction, and pain score; RESULTS: Of 505 included patients, 405 received a postoperative prescription and 67 continued use at 2-weeks. These 67 patients reported lower bMHQ, lower satisfaction, and higher postoperative pain compared to those that discontinued. Multivariable regressions showed that receiving postoperative prescriptions did not significantly influence outcomes or satisfaction. However, remaining on the prescription at 2 weeks was associated with significantly lower bMHQ scores, particularly in patients reporting less pain UR - https://dx.doi.org/10.1177/15589447211064365 ER -