Spontaneous labor curves in women with pregnancies complicated by diabetes.
- 2012
Available online through MWHC library: 2013 to the present
CONCLUSIONS: Labor curves of women with preDM and GDM approximate those of non-diabetics, regardless of BMI, birth weight, or parity. METHODS: A retrospective analysis was performed from 228,668 deliveries between 2002-2008 from the Consortium of Safe Labor (National Institute of Child Health and Human Development, National Institutes of Health). Patients with spontaneous onset of labor from 37 0/7-41 6/7 weeks gestation were included (71,282) and classified as nulliparous or multiparous. Pregnancies were further subdivided regarding presence of preexisting diabetes (preDM) or gestational diabetes (GDM) and normal controls. Labor curves were created matching for body mass index (BMI) and neonatal birth weight. Statistical analysis was performed on descriptive variables using (2) with significance designated as p<0.05. OBJECTIVE: To test the hypothesis that the first stage of labor will be longer in nulliparous and multiparous women with diabetes compared to non-diabetic counterparts. RESULTS: Among nulliparous patients, there were 118 women with preDM and 475 women with GDM; 25,771 patients served as normal controls. Among multiparous women, there were 311 with preDM, 1,079 with GDM and 43,528 in the control group. Although differences in dilatation rates were observed in nulliparous and multiparous women with and without diabetes, labor progression was similar between the subgroups when matched for maternal BMI and birth weight.
English
1476-4954
*Labor, Obstetric/ph [Physiology] *Pregnancy in Diabetics/pp [Physiopathology] Adult Birth Weight Body Mass Index Cohort Studies Diabetes, Gestational/pp [Physiopathology] Female Fetal Macrosomia/ep [Epidemiology] Humans Infant, Newborn National Institutes of Health (U.S.) Parity Pregnancy Retrospective Studies Time Factors United States
MedStar Health Research Institute MedStar Washington Hospital Center
Obstetrics and Gynecology, Maternal-Fetal Medicine
Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't