TY  - BOOK
AU  - Campia, Umberto
TI  - The possible role of glutathione-S-transferase activity in diabetic nephropathy. [Review]
SN  - 0394-6320
PY  - 2015///
KW  - *Diabetes Complications/me [Metabolism]
KW  - *Diabetic Nephropathies/me [Metabolism]
KW  - *Glutathione Transferase/me [Metabolism]
KW  - Biomarkers/me [Metabolism]
KW  - Humans
KW  - Kidney Failure, Chronic/me [Metabolism]
KW  - Renal Insufficiency, Chronic/me [Metabolism]
KW  - MedStar Heart & Vascular Institute
KW  - Letter
KW  - Review
N2  - Copyright © The Author(s) 2015; The most common cause of end stage renal disease is diabetic nephropathy. An early diagnosis may allow an intervention to slow down disease progression. Recently, it has been hypothesized that glutathione-S-transferase (GST) activity may be a marker of severity of chronic kidney disease. In particular, a lower GST activity is present in healthy subjects compared to patients with nephropathy. In the present review we illustrate the scientific evidence underlying the possible role of GST activity in the development of diabetic nephropathy and we analyze its usefulness as a possible early biomarker of this diabetic complication.
UR  - https://dx.doi.org/10.1177/0394632015572564
ER  -