TY  - BOOK
AU  - Ganguli, Anirban
TI  - Obstructive Uropathy as an Initial Presentation of Primary Myelofibrosis: Case Report and Review of Literature
SN  - 0971-4502
PY  - 2016///
KW  - PubMed-not-MEDLINE -- Not indexed
KW  - MedStar Washington Hospital Center
KW  - Medicine/Nephrology
KW  - Journal Article
N2  - Primary myelofibrosis (PMF) is a rare hematological disorder associated with progressive cytopenia and extra-medullary hematopoiesis. Acute kidney injury in this disease has been reported from diverse etiologies such as renal and peri-renal extramedullary hematopoiesis and tumor lysis syndrome. We report a patient who presented with obstructive uropathy from uric acid stones who was incidentally diagnosed with PMF during workup for persistent thrombocytosis and leukocytosis. Marrow histopathology was unique in presenting features of early PMF despite clinical picture mimicking essential thrombocythemia. Despite a common background of hyperuricemia in myeloproliferative neoplasms, AKI resulting from urate nephrolithiasis has seldom been reported in PMF. Published data on this association and clinical management is reviewed briefly
UR  - https://dx.doi.org/10.1007/s12288-016-0679-6
ER  -