Impact of baseline mitral regurgitation on short- and long-term outcomes following transcatheter aortic valve replacement.
- 2016
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
BACKGROUND: The prevalence of concomitant significant mitral regurgitation (MR) in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) ranges from 2% to 33%. The impact of significant MR on post-TAVR outcomes remains controversial. CONCLUSIONS: Moderate or greater MR in patients undergoing TAVR is associated with a higher 30-day but not 1-year mortality. A majority of the patients demonstrated significant improvement in MR following TAVR. Copyright � 2016. Published by Elsevier Inc. METHODS: The data from a cohort of patients with symptomatic severe AS undergoing TAVR at out institution were retrospectively analyzed. The last transthoracic echocardiogram (TTE) before the index TAVR procedure was selected as the baseline assessment of the degree of MR. The total study cohort (N = 589) was divided into 2 groups: significant >moderate MR (n = 68) versus nonsignificant moderate MR on mortality at short- and long-term follow-up periods. RESULTS: Patients with >moderate MR had a higher mortality rate versus patients with moderate group, 62.5% and 77.7% of patients had improved to