TY - BOOK AU - Venkatesan, Krishnan TI - Clinical and Patient-Reported Outcomes of One-Sided Anterior Urethroplasty for Long-Segment or Panurethral Strictures SN - 0090-4295 PY - 2018/// KW - *Patient Reported Outcome Measures KW - *Urethra/su [Surgery] KW - *Urethral Stricture/su [Surgery] KW - Adult KW - Aged KW - Aged, 80 and over KW - Humans KW - Male KW - Middle Aged KW - Mouth Mucosa/tr [Transplantation] KW - Retrospective Studies KW - Sexual Behavior/ph [Physiology] KW - Treatment Outcome KW - Urethral Stricture/pa [Pathology] KW - Urination KW - Urologic Surgical Procedures, Male/mt [Methods] KW - Young Adult KW - MedStar Washington Hospital Center KW - Urology KW - Journal Article N1 - Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007 N2 - CONCLUSIONS: Durable patency in most patients is demonstrated in this study. Patient-reported outcome measures indicate an improvement in urinary function and moderate effect on sexual function. Transient penile chordee was evident in 25% of patients. Copyright (c) 2017. Published by Elsevier Inc; METHODS: Patients from four institutions after single-stage repairs for long-segment urethral strictures (> 8 cm) from January 2002 to April 2016 were reviewed. Technique described by Kulkarni et al was used in all cases. Clinical outcomes included uroflowmetry (Qmax), post-void residuals (PVR). PROMs included IPSS survey, SHIM, Male Sexual Health Questionnaire (MSHQ-EjS) and Global Response Assessment questionnaire (GRA) to measure voiding, sexual, ejaculatory symptoms and overall improvement respectively; OBJECTIVES: To evaluate clinical and patient-reported urinary and sexual outcomes after a long-segment stricture repair using the one-sided urethral dissection, penile invagination and dorsal BMG onlay technique described by Kulkarni; RESULTS: Seventy-three patients with a minimum of 12-months follow-up were included. The mean age and stricture length were 56(21-80) years and 13.6(8-21) cm respectively. At a mean follow-up of 44(12-162) months, 9/73(12%) strictures recurred. The mean baseline IPSS score of 23(7-24) decreased to 10(1-17) on follow-up (p <0.001). 8/42 patients (21.4%) reported an increase and 6/42 patients (14.3%) decrease in SHIM following urethroplasty. Ejaculatory function on MSHQ-EjS improved after urethroplasty from 8 pre-operatively to 11 post-operatively (p<0.004). All patients reported improvement after urethroplasty on GRA questionnaire. Post-void dribbling and chordee occurred in 45% and 25% of patients respectively UR - https://dx.doi.org/10.1016/j.urology.2017.08.029 ER -