TY  - BOOK
AU  - Bodendorfer, Blake M
TI  - Do 25-Hydroxyvitamin D Levels Correlate With Fracture Complications?
SN  - 0890-5339
PY  - 2016///
KW  - *Fractures, Bone/bl [Blood]
KW  - *Fractures, Bone/ep [Epidemiology]
KW  - *Postoperative Complications/bl [Blood]
KW  - *Postoperative Complications/ep [Epidemiology]
KW  - *Reoperation/ut [Utilization]
KW  - *Vitamin D/aa [Analogs & Derivatives]
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Biomarkers/bl [Blood]
KW  - Bone Density Conservation Agents/tu [Therapeutic Use]
KW  - Calcium/tu [Therapeutic Use]
KW  - Female
KW  - Fractures, Bone/dt [Drug Therapy]
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Missouri/ep [Epidemiology]
KW  - Postoperative Complications/pc [Prevention & Control]
KW  - Prevalence
KW  - Prognosis
KW  - Prospective Studies
KW  - Reproducibility of Results
KW  - Risk Assessment/mt [Methods]
KW  - Sensitivity and Specificity
KW  - Statistics as Topic
KW  - Treatment Outcome
KW  - Vitamin D/bl [Blood]
KW  - Vitamin D/tu [Therapeutic Use]
KW  - Young Adult
KW  - MedStar Washington Hospital Center
KW  - Surgery/Orthopaedic Surgery
KW  - Controlled Clinical Trial
KW  - Journal Article
N1  - Available online from MWHC library: 1996 - present
N2  - CONCLUSIONS: Serum 25(OH)D levels did not significantly affect the likelihood of fracture healing complications requiring surgery or any nonorthopaedic injury-related surgery; DESIGN: Retrospective case series; INTERVENTION: All patients received 1000 IU of vitamin D3 and 1500 mg of calcium daily. Vitamin D deficient and insufficient patients also received 50,000 IU of ergocalciferol (vitamin D2) weekly until 25(OH)D levels normalized or fractures healed; LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence; MAIN OUTCOME MEASUREMENTS: fracture complications and 25(OH)D levels; OBJECTIVES: To determine the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and the likelihood of postoperative complications and fracture reoperation rate in orthopaedic trauma patients receiving vitamin D and calcium supplementation; PATIENTS: All orthopaedic trauma patients-18 years or older-over a 20-month period were included with available initial and repeat 25(OH)D serum levels. In total, 201 patients met inclusion criteria; RESULTS: Fifteen patients experienced postoperative healing complications. There was no significant difference between initial (P = 0.92) or repeat (P = 0.91) 25(OH)D levels between patients with and without fracture healing complications. Twenty-eight patients required repeat orthopaedic surgery. There was no significant difference between initial (P = 0.62) or repeat (P = 0.18) 25(OH)D levels between patients who did or did not require repeat orthopaedic surgery. There was no significant difference between initial (P = 0.66) or repeat (P = 0.89) 25(OH)D levels between patients who did or did not require nonorthopaedic surgery; SETTING: Level I trauma center, Midwestern United States
UR  - https://dx.doi.org/10.1097/BOT.0000000000000639
ER  -