TY  - BOOK
AU  - Modisett, Katharine L
TI  - Outcomes in Cardiac Arrest Patients due to Toxic Exposure Treated with Therapeutic Hypothermia
SN  - 1556-9039
PY  - 2016///
KW  - *Cardiotoxins/to [Toxicity]
KW  - *Heart Arrest/th [Therapy]
KW  - *Hypothermia, Induced/ae [Adverse Effects]
KW  - *Poisoning/pp [Physiopathology]
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Analgesics, Opioid/po [Poisoning]
KW  - Analgesics, Opioid/to [Toxicity]
KW  - Benzodiazepines/po [Poisoning]
KW  - Cocaine/to [Toxicity]
KW  - Combined Modality Therapy/ae [Adverse Effects]
KW  - Female
KW  - Heart Arrest/ep [Epidemiology]
KW  - Heart Arrest/et [Etiology]
KW  - Heart Arrest/pc [Prevention & Control]
KW  - Hospitals, Teaching
KW  - Humans
KW  - Incidence
KW  - Male
KW  - Middle Aged
KW  - North Carolina/ep [Epidemiology]
KW  - Poisoning/ep [Epidemiology]
KW  - Registries
KW  - Retrospective Studies
KW  - Secondary Prevention
KW  - Young Adult=520  \\
KW  - The incidence and outcome of patients who undergo therapeutic hypothermia (TH) after toxin-induced cardiac arrest (TICA) is not previously described. Our study aimed to describe the incidence, epidemiologic characteristics, and outcomes of patients who experience TICA in a dedicated clinical pathway for post-cardiac arrest care between November 2007 and February 2013. All patients were treated in an evidence-based clinical pathway that included TH. Database and medical records were independently reviewed by investigators to ascertain TICA. TICA was defined as cardiac arrest (CA) directly and immediately caused by a xenobiotic exposure. All patients were enrolled at Carolinas Medical Center, an urban 874-bed teaching hospital that serves as a regional cardiac resuscitation center. All patients were adult victims of cardiac arrest who had obtained return of spontaneous circulation and were enrolled in a clinical pathway for post-cardiac arrest care that included TH. Three hundred eighty-nine patients underwent treatment following CA during the study period and 48 (12 %) were deemed TICA. Patients who suffered TICA were slightly younger, less likely to have an initial shockable rhythm, and less likely to receive bystander CPR as compared to non-toxic cases. TICA accounted for a significant proportion of patients in this study. Additional, larger studies are needed to fully elucidate the optimal role for TH in TICA
KW  - MedStar Washington Hospital Center
KW  - Medicine/Pulmonary-Critical Care
KW  - Journal Article
UR  - https://dx.doi.org/10.1007/s13181-016-0536-x
ER  -