TY - BOOK AU - Benson, Richard T AU - Hsia, Amie W TI - Perfusion Deficits and Association with Clinical Outcome in Patients with Anterior Choroidal Artery Stroke SN - 1052-3057 PY - 2017/// KW - *Cerebrovascular Circulation KW - *Choroid Plexus/bs [Blood Supply] KW - *Stroke/pp [Physiopathology] KW - Aged KW - Aged, 80 and over KW - Diffusion Magnetic Resonance Imaging KW - Disability Evaluation KW - District of Columbia KW - Female KW - Humans KW - Male KW - Maryland KW - Middle Aged KW - Patient Discharge KW - Perfusion Imaging/mt [Methods] KW - Recovery of Function KW - Risk Factors KW - Stroke/dg [Diagnostic Imaging] KW - Stroke/th [Therapy] KW - Thrombolytic Therapy KW - Treatment Outcome KW - MedStar Washington Hospital Center KW - Neurology KW - Journal Article N2 - BACKGROUND AND PURPOSE: Anterior choroidal artery (AChA) strokes have a varied pattern of tissue injury, prognosis, and clinical outcome. It is unclear whether perfusion deficit in AChA stroke is associated with the clinical outcome. This study aims to determine the frequency of perfusion abnormalities in AChA stroke and association with clinical outcome; CONCLUSIONS: Two thirds of patients with an AChA stroke have a perfusion deficit on MRI, higher admission NIHSS, and larger DWI lesion size at presentation; Copyright � 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved; METHODS: The study cohort was derived from ischemic stroke patients admitted to 2 stroke centers between July 2001 and July 2014. All patients received an acute magnetic resonance imaging (MRI) scan. Patients with ischemic stroke restricted to the AChA territory were included in the study. Lesion size was measured as the largest diameter on diffusion-weighted imaging (DWI) or apparent diffusion coefficient and divided into 2 groups (<20mm or>20mm). Group comparisons were performed among patients with and without perfusion abnormalities and based on diffusion diameter. Favorable clinical outcome was defined as discharge to home; RESULTS: A total of 120 patients were included in the study. Perfusion deficits were identified in 67% of patients. The admission National Institutes of Health Stroke Scale (NIHSS) was higher in patients with perfusion abnormalities (P=.027). Diameter lesion size on DWI was larger among patients with a perfusion deficit median [interquartile range], 1.63 [1.3-2.0], as compared with those without, 1.18 [1.0-1.7], P<.0001. Patients with a perfusion deficit were less likely to be discharged to home than those without (36% versus 60%, P=.013) UR - https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.04.001 ER -