TY  - BOOK
AU  - Graham, Autumn
AU  - Kappler, Shane
TI  - Thrombotic Microangiopathies (TTP, HUS, HELLP). [Review]
SN  - 0889-8588
PY  - 2017///
KW  - *Emergency Medical Services/mt [Methods]
KW  - *Thrombotic Microangiopathies
KW  - Disseminated Intravascular Coagulation/bl [Blood]
KW  - Disseminated Intravascular Coagulation/di [Diagnosis]
KW  - Disseminated Intravascular Coagulation/pp [Physiopathology]
KW  - Disseminated Intravascular Coagulation/th [Therapy]
KW  - Humans
KW  - Platelet Count
KW  - Purpura, Thrombocytopenic, Idiopathic/bl [Blood]
KW  - Purpura, Thrombocytopenic, Idiopathic/di [Diagnosis]
KW  - Purpura, Thrombocytopenic, Idiopathic/pp [Physiopathology]
KW  - Purpura, Thrombocytopenic, Idiopathic/th [Therapy]
KW  - Thrombotic Microangiopathies/bl [Blood]
KW  - Thrombotic Microangiopathies/di [Diagnosis]
KW  - Thrombotic Microangiopathies/pp [Physiopathology]
KW  - Thrombotic Microangiopathies/th [Therapy]
KW  - MedStar Washington Hospital Center
KW  - Emergency Medicine
KW  - Journal Article
KW  - Review
N1  - Available online from MWHC library: 1996 - present
N2  - Copyright (c) 2017 Elsevier Inc. All rights reserved; Thrombocytopenia, strictly defined as a platelet count less than 150,000, is common in the emergency department. Recognition, diagnostic investigation, and proper disposition of a thrombocytopenic patient are imperative. One group of disorders leading to thrombocytopenia is the thrombotic microangiopathies, hallmarked by platelet destruction. These thrombotic microangiopathies include thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzyme levels, low platelet count (HELLP), which should be distinguished from similar disease processes such as immune thrombocytopenia (ITP), disseminated intravascular coagulation (DIC) and heparin induced thrombocytopenia (HIT). In this article, clinical presentations, pathophysiology, diagnostic workup, management plans, complications, and dispositions are addressed for this complex group of platelet disorders
UR  - https://dx.doi.org/10.1016/j.hoc.2017.08.010
ER  -