Case of acute mixed liver injury due to hypothyroidism. - 2018

Copyright (c) BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. The effects of hypothyroidism on the liver are not well understood. A 77-year-old woman with Hashimoto's thyroiditis had stopped taking levothyroxine on her own for 6months. Her thyroid stimulating hormone (TSH) level was consistent with severe hypothyroidism. She resumed thyroid replacement therapy. The following month, her liver function tests were significantly elevated. Seven weeks after resumption of therapy, her TSH and liver tests had returned to normal. We attribute the mixed hepatocellular injury to hypothyroidism that resolved on correction of the hypothyroid state. This case reminds us that thyroid disease should be considered when evaluating acute liver injury.


English

1757-790X

10.1136/bcr-2017-222373 [doi] bcr-2017-222373 [pii]


IN PROCESS -- NOT YET INDEXED


MedStar Washington Hospital Center


Medicine/Internal Medicine


Journal Article