TY - BOOK AU - Polland, Allison AU - Venkatesan, Krishnan AU - Zeymo, Alexander TI - Comparison of Correlated Comorbidities in Male and Female Sexual Dysfunction: Findings From the Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3) SN - 1743-6095 PY - 2018/// KW - *Life Style KW - *Sexual Dysfunction, Physiological/ep [Epidemiology] KW - Adolescent KW - Adult KW - Age Factors KW - Aged KW - Attitude KW - Cardiovascular Diseases/ep [Epidemiology] KW - Diabetes Mellitus/ep [Epidemiology] KW - Female KW - Health Surveys KW - Humans KW - Male KW - Menopause KW - Mental Disorders/ep [Epidemiology] KW - Middle Aged KW - Multivariate Analysis KW - Obesity/ep [Epidemiology] KW - Prospective Studies KW - Pulmonary Disease, Chronic Obstructive/ep [Epidemiology] KW - Sampling Studies KW - Sexual Behavior KW - Smoking/ep [Epidemiology] KW - Urinary Incontinence/ep [Epidemiology] KW - MedStar Health Research Institute KW - MedStar Washington Hospital Center KW - Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive Surgery KW - Urology KW - Journal Article N2 - AIM: To assess whether sexual function in men and women is correlated with similar comorbidities; BACKGROUND: Many of the same mechanisms involved in the sexual arousal-response system in men exist in women and can be affected by underlying general medical conditions; CLINICAL IMPLICATIONS: Physicians should be aware of the correlation between medical comorbidities and sexual dysfunction in women and men and should ask patients about specific symptoms that might be associated with underlying medical conditions; CONCLUSION: Multiple medical comorbidities are associated with sexual dysfunction not only in men but also in women. Polland A, Davis M, Zeymo A, et al. Comparison of Correlated Comorbidities in Male and Female Sexual Dysfunction: Findings From the Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). J Sex Med 2018;15:678-686; Copyright (c) 2018. Published by Elsevier Inc; METHODS: This study was a secondary analysis of the 3rd National Survey of Sexual Attitudes and Lifestyles (Natsal-3), a prospective stratified probability sample of British individuals 16 to 74 years old interviewed from 2010 to 2012. We assessed for an association between sexual function and the following comorbidities: heart attack, heart disease, hypertension, stroke, diabetes, chronic lung disease, depression, other mental health conditions, other neurologic conditions, obesity, menopause, incontinence, smoking status, and age; OUTCOME: An association was found between multiple medical comorbidities and sexual dysfunction in women and in men; RESULTS: 6,711 women and 4,872 men responded to the survey, were in a relationship, and reported sexual activity in the past year. The average age of the women was 35.4 +/- 14.1 and that of the men was 36.8 +/- 15.6. There was an association between sexual function and all variables assessed except for chronic lung disease, heart attack, and incontinence in women compared with stroke, other neurologic conditions, incontinence, and smoking status in men. Comorbidities associated with erectile dysfunction included depression, diabetes, and other heart disease, whereas comorbidities associated with difficulty with lubrication included depression and other heart disease. Menopause was predictive of sexual dysfunction. Male sexual function appeared to decline after 45.5 years of age; STRENGTHS AND LIMITATIONS: Use of a stratified probability sample compared with a convenience sample results in capturing of associations representative of the population. Inclusion of multiple comorbidities in the multivariate analysis allows us to understand the effects of several variables on sexual function. Although this study shows only an association, further research could determine whether there is a causal relation between comorbidities and sexual dysfunction in women UR - https://dx.doi.org/10.1016/j.jsxm.2018.02.023 ER -