TY  - BOOK
AU  - Baker, Nevin C
AU  - Escarcega, Ricardo O
AU  - Lhermusier, Thibault
AU  - Magalhaes, Marco A
AU  - Minha, Sa'ar
AU  - Pendyala, Lakshmana K
AU  - Pichard, Augusto D
AU  - Satler, Lowell F
AU  - Torguson, Rebecca
AU  - Waksman, Ron
TI  - Does direct stenting with drug-eluting stents improve outcome? A meta-analysis of 10,900 patients
SN  - 1522-1946
PY  - 2017///
KW  - *Angioplasty, Balloon/is [Instrumentation]
KW  - *Coronary Artery Disease/th [Therapy]
KW  - *Drug-Eluting Stents
KW  - *Percutaneous Coronary Intervention/is [Instrumentation]
KW  - Aged
KW  - Angioplasty, Balloon/ae [Adverse Effects]
KW  - Angioplasty, Balloon/mo [Mortality]
KW  - Chi-Square Distribution
KW  - Coronary Artery Disease/dg [Diagnostic Imaging]
KW  - Coronary Artery Disease/mo [Mortality]
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Odds Ratio
KW  - Percutaneous Coronary Intervention/ae [Adverse Effects]
KW  - Percutaneous Coronary Intervention/mo [Mortality]
KW  - Risk Assessment
KW  - Risk Factors
KW  - Treatment Outcome
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
N1  - Available online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006
N2  - BACKGROUND: DS has been associated with improved outcomes in the bare-metal stent era. Although DS with DES implantation has been increasingly adopted in clinical practice, its safety and effectiveness remain controversial; CONCLUSIONS: DS with DES is safe and may be associated with better outcomes in selected patients. � 2016 Wiley Periodicals, Inc; Copyright � 2016 Wiley Periodicals, Inc; METHODS: The search criteria identified 546 studies in the Medline/PubMed, Cochrane, and EMBASE databases from 2001 to July 2014. From these, seven studies totaling 10,900 patients were selected. Summarized estimates [odds ratio (OR) and 95% confidence intervals] were obtained using a random-effects model. The primary outcomes were a composite of major adverse cardiac events (MACE), including all-cause death, myocardial infarction (MI), and repeat revascularization. The secondary outcomes included a composite of death and MI and the rates of target lesion revascularization (TLR); OBJECTIVES: The aim of this study is to summarize the outcomes of patients undergoing direct stenting (DS) with drug-eluting stents (DES) compared to those who underwent balloon predilatation; RESULTS: Overall, 4101 (38%) and 6799 (62%) patients underwent DS with DES and balloon pre-dilatation, respectively. DS with DES reduced the likelihood of MACE (OR: 0.81 [0.71-0.93]). Additionally, DS with DES was associated with reduced rates of death/MI (OR: 0.76 [0.62-0.92]), and TLR (OR: 0.66 [0.44-0.98])
UR  - https://dx.doi.org/10.1002/ccd.26861
ER  -