TY  - BOOK
AU  - Goyal, Munish
AU  - Hawley, Kristy L
AU  - Mazer-Amirshahi, Maryann
AU  - Umar, Suleman A
TI  - U.S. drug shortages for medications used in adult critical care (2001-2016)
SN  - 0883-9441
PY  - 2017///
KW  - *Critical Care/ut [Utilization]
KW  - *Emergency Service, Hospital/sn [Statistics & Numerical Data]
KW  - *Pharmacy Service, Hospital/sn [Statistics & Numerical Data]
KW  - *Prescription Drugs/sd [Supply & Distribution]
KW  - Drug Substitution
KW  - Humans
KW  - Utah
KW  - MedStar Union Memorial Hospital
KW  - MedStar Washington Hospital Center
KW  - Emergency Medicine
KW  - Medicine/Pulmonary Critical Care
KW  - Surgery
KW  - Journal Article
N1  - Available online through MWHC library: 2012 - present
N2  - CONCLUSIONS: Although the number of new shortages peaked in 2011 and is now declining, there remain a substantial number of active shortages impacting critical care drugs; Copyright 2017. Published by Elsevier Inc; MATERIALS AND METHODS: Shortages within the scope of critical care were identified using data from the University of Utah Drug Information Services. Shortage characteristics were described using standard descriptive statistics and regression analysis; PURPOSE: We describe trends in U.S. shortages impacting critical care drugs from 2001 to 2016; RESULTS: Of 1969 shortages reported, 1004 (51%) were for drugs used in critical care. New shortages fell from 2001 to 2004, then increased, peaking in 2011 (116). For critical care shortages, 247 (24.6%) involved drugs used for high acuity conditions. The majority of drugs on shortage were parenteral, (720; 71.7%) and 393 (39.1%) were single source drugs. Alternatives were available for 887 (88.3%) drugs, although 250 (24.9%) alternatives were impacted by shortages. Infectious disease drugs were the most common drugs on shortage, with 200 (19.9%) shortages, with a median duration of 7.7months (IQR=2.8-17.3). By the end of the study, 896 (89.2%) shortages were resolved and 108 (10.8%) remained active. The median duration for active shortages was 13.6months (IQR=5.8-58.4) while the duration for resolved shortages was 7.2months (IQR=2.8-17.3)
UR  - https://dx.doi.org/10.1016/j.jcrc.2017.06.005
ER  -