TY  - BOOK
AU  - Hashemi, Shar
AU  - Parikh, Pranay
TI  - Selective Thumb Carpometacarpal Joint Denervation for Painful Arthritis: Clinical Outcomes and Cadaveric Study
SN  - 0363-5023
PY  - 2018///
KW  - IN PROCESS -- NOT YET INDEXED
KW  - Curtis National Hand Center
KW  - Journal Article
N1  - Available in print through MWHC library: 1999 - 2002, Available online from MWHC library: 1995 - present
N2  - CONCLUSIONS: Selective denervation of the CMC joint is an effective approach to treat pain and alleviate impairment associated with CMC arthritis. The procedure is well tolerated, with faster recovery as compared with trapeziectomy. Branches arising from the lateral antebrachial cutaneous nerve, palmar cutaneous branch of the median nerve, and radial sensory nerve can be identified and resected with a single-incision Wagner approach; Copyright (c) 2018 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved; METHODS: Cadaveric dissections were performed in 10 fresh upper extremities to better define the innervation patterns to the CMC joint and guide the surgical approach for CMC joint denervation. Histologic confirmation of candidate nerves was performed with hematoxylin and eosin staining. Results from a series of 12 patients with symptomatic thumb CMC arthritis who underwent selective denervation were retrospectively evaluated to determine the safety and efficacy of this treatment approach. Differences in preoperative and postoperative measurements of grip and key-pinch strength as well as subjective reporting of symptoms were compared; PURPOSE: To determine the innervation pattern to the thumb carpometacarpal (CMC) joint and assess the safety and efficacy of selective joint denervation for the treatment of pain and impairment associated with thumb CMC arthritis; RESULTS: Nerve branches to the thumb CMC joint were found to arise from the lateral antebrachial cutaneous nerve (10 of 10 specimens), the palmar cutaneous branch of the median nerve (7 of 10 specimens), and the radial sensory nerve (4 of 10 specimens). With an average follow-up time of 15 months, 11 of 12 patients (92%) reported complete or near-complete relief of pain. Average improvements in grip and lateral key-pinch strength were 4.1 +/- 3.0 kg (18% +/- 12% from baseline) and 1.7 +/- 0.5 kg (37% +/- 11% from baseline), respectively. One patient experienced the onset of new pain consistent with a neuroma that resolved with steroid injection. All patients were released to light activity at 1 week after surgery, and all activity restrictions were lifted by 6 weeks after surgery; TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic V
UR  - https://dx.doi.org/10.1016/j.jhsa.2018.04.030
ER  -