Intravascular large B-cell lymphoma presenting as multiple stroke: A case report. 

 -  2018 
<br/><br/>Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 
<br/><br/> CASE PRESENTATION: We report an interesting case of IVLBCL presenting as bilateral strokes. The diagnosis was made by a random skin biopsy, which confirmed IVLBCL. The patient was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP).Neurological symptoms improved with R-CHOP. Repeat magnetic resonance imaging (MRI) of the brain showed improvement of the prior lesions.  CONCLUSION: IVLBCL is an aggressive disease with high mortality. Timely diagnosis and treatment can be lifesaving.  INTRODUCTION: Intravascular large B-cell lymphoma (IVLBCL) is an uncommon disease with a poor prognosis if not diagnosed early. It can present with central nervous system (CNS) manifestations. The diagnosis of IVCBCL is difficult to make given its varied clinical manifestations and the lack of a specific diagnostic modality. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>0025-7974 
<br/><br/><label>Standard No.: </label>00005792-201810120-00087 [pii] 10.1097/MD.0000000000012793 [doi] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Lymphoma, Large B-Cell, Diffuse/di [Diagnosis]<br/>*Lymphoma, Large B-Cell, Diffuse/pa [Pathology]<br/>*Stroke/di [Diagnosis]<br/>*Stroke/pa [Pathology]<br/>*Vascular Neoplasms/di [Diagnosis]<br/>*Vascular Neoplasms/pa [Pathology]<br/>Antibodies, Monoclonal, Murine-Derived<br/>Antineoplastic Combined Chemotherapy Protocols<br/>Cyclophosphamide<br/>Diagnosis, Differential<br/>Doxorubicin<br/>Female<br/>Humans<br/>Lymphoma, Large B-Cell, Diffuse/dt [Drug Therapy]<br/>Middle Aged<br/>Prednisone<br/>Vascular Neoplasms/dt [Drug Therapy]<br/>Vincristine
<br/><br/><label>Subjects--Geographic Terms: </label><br/>Medstar Franklin Square Medical Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Pulmonary and Critical Care Medicine
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article