TY - BOOK AU - Selinger, Stephen TI - Intravascular large B-cell lymphoma presenting as multiple stroke: A case report SN - 0025-7974 PY - 2018/// KW - *Lymphoma, Large B-Cell, Diffuse/di [Diagnosis] KW - *Lymphoma, Large B-Cell, Diffuse/pa [Pathology] KW - *Stroke/di [Diagnosis] KW - *Stroke/pa [Pathology] KW - *Vascular Neoplasms/di [Diagnosis] KW - *Vascular Neoplasms/pa [Pathology] KW - Antibodies, Monoclonal, Murine-Derived KW - Antineoplastic Combined Chemotherapy Protocols KW - Cyclophosphamide KW - Diagnosis, Differential KW - Doxorubicin KW - Female KW - Humans KW - Lymphoma, Large B-Cell, Diffuse/dt [Drug Therapy] KW - Middle Aged KW - Prednisone KW - Vascular Neoplasms/dt [Drug Therapy] KW - Vincristine KW - Medstar Franklin Square Medical Center KW - Pulmonary and Critical Care Medicine KW - Journal Article N1 - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 N2 - CASE PRESENTATION: We report an interesting case of IVLBCL presenting as bilateral strokes. The diagnosis was made by a random skin biopsy, which confirmed IVLBCL. The patient was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP).Neurological symptoms improved with R-CHOP. Repeat magnetic resonance imaging (MRI) of the brain showed improvement of the prior lesions; CONCLUSION: IVLBCL is an aggressive disease with high mortality. Timely diagnosis and treatment can be lifesaving; INTRODUCTION: Intravascular large B-cell lymphoma (IVLBCL) is an uncommon disease with a poor prognosis if not diagnosed early. It can present with central nervous system (CNS) manifestations. The diagnosis of IVCBCL is difficult to make given its varied clinical manifestations and the lack of a specific diagnostic modality UR - https://dx.doi.org/10.1097/MD.0000000000012793 ER -