02866nam a22004697a 4500
181214s20182018 xxu||||| |||| 00| 0 eng d
0960-7404
10.1016/j.suronc.2018.08.005 [doi]
S0960-7404(18)30055-0 [pii]
Ovid MEDLINE(R)
30449489
Sclerosing encapsulating peritonitis as a potential complication of cytoreductive surgery and HIPEC: Clinical features and results of treatment in 4 patients.
Surgical Oncology. 27(4):657-662, 2018 Dec.
Surg Oncol. 27(4):657-662, 2018 Dec.
Surgical oncology
2018
FY2019
ppublish
2018-12-14
Copyright (c) 2018 Elsevier Ltd. All rights reserved.
Sclerosing encapsulating peritonitis (SEP) is a rare entity characterized by encapsulation of the small bowel and/or the colon by a fibrous tissue that forms a shell. Intraperitoneal chemotherapy (IPC) has been reported to be a potential causative factor of secondary SEP. However, few studies have reported on secondary SEP related to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Here, we review results from four clinical cases of SEP associated with CRS and HIPEC. In all four patients, additional surgery was necessary to alleviate recurrent episodes of small bowel obstruction. These obstructions can occur as early as several weeks after CRS plus HIPEC or as late as 3 years after treatment. Of utmost importance is the prevention of fistulization which can result in enteric contamination of the peritoneal space. To date, no solution to SEP has been identified except additional surgery but it is evident that these reoperative experiences are difficult for both surgeon and patient. The etiopathogenesis of SEP in this setting remains unknown but it is clear that it is related to chronic inflammation of the peritoneum. Large studies are needed to identify the incidence and potential common causes of SEP after CRS and HIPEC.
English
*Cytoreduction Surgical Procedures/ae [Adverse Effects]
*Peritoneal Neoplasms/co [Complications]
*Peritoneal Neoplasms/su [Surgery]
*Peritonitis/et [Etiology]
*Peritonitis/pa [Pathology]
Adult
Aged
Female
Humans
Male
Middle Aged
Peritoneal Neoplasms/sc [Secondary]
Prognosis
Washington Cancer Institute
Journal Article
Sugarbaker, Paul H
Liberale G, Sugarbaker PH
https://dx.doi.org/10.1016/j.suronc.2018.08.005
https://dx.doi.org/10.1016/j.suronc.2018.08.005
ART
Article
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Article
authcat
authcat
2018-12-14
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30449489
30449489
2018-12-14
2018-12-14
ART
3950
3950