TY  - BOOK
AU  - Walker, Kathryn A
TI  - Safe and Appropriate Use of Methadone in Hospice and Palliative Care: Expert Consensus White Paper
SN  - 0885-3924
PY  - 2019///
KW  - *Analgesics, Opioid/tu [Therapeutic Use]
KW  - *Hospice Care
KW  - *Methadone/tu [Therapeutic Use]
KW  - *Pain/dt [Drug Therapy]
KW  - *Palliative Care
KW  - Analgesics, Opioid/ae [Adverse Effects]
KW  - Humans
KW  - Methadone/ae [Adverse Effects]
KW  - MedStar Health Research Institute
KW  - Journal Article
N1  - Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
N2  - Copyright (c) 2018 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved; Methadone has several unique characteristics that make it an attractive option for pain relief in serious illness, but the safety of methadone has been called into question after reports of a disproportionate increase in opioid-induced deaths in recent years. The American Pain Society (APS), College on Problems of Drug Dependence, and the Heart Rhythm Society collaborated to issue guidelines on best practices to maximize methadone safety and efficacy, but guidelines for the end-of-life scenario have not yet been developed. A panel of 15 interprofessional hospice and palliative care experts from the US and Canada convened in February 2015 to evaluate the APS methadone recommendations for applicability in the hospice and palliative care setting. The goal was to develop guidelines for safe and effective management of methadone therapy in hospice and palliative care. This article represents the consensus opinion of the hospice and palliative care experts for methadone use at end of life, including guidance on appropriate candidates for methadone, detail in dosing, titration, and monitoring of patients' response to methadone therapy
UR  - https://dx.doi.org/10.1016/j.jpainsymman.2018.12.001
ER  -