03982nam a22006377a 4500
190314s20192019 xxu||||| |||| 00| 0 eng d
0002-9149
10.1016/j.amjcard.2018.12.029 [doi]
S0002-9149(19)30032-3 [pii]
Ovid MEDLINE(R)
30683424
Serial 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side-Branch by Second-Generation Drug-Eluting Absorbable Metal Scaffold (from the BIOSOLVE-II Trial).
American Journal of Cardiology. 123(7):1044-1051, 2019 04 01.
Am J Cardiol. 123(7):1044-1051, 2019 04 01.
Am J Cardiol. 2019 Jan 04
The American journal of cardiology
2019
FY2019
aheadofprint
2019-03-14
American Journal of Cardiology. 2019 Jan 04
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
Copyright (c) 2019. Published by Elsevier Inc.
Second-generation drug-eluting absorbable metal scaffold (DREAMS 2G) is used for treating coronary lesions. However, the natural history of the jailed side-branch (SB) after DREAMS 2G implantation remains to be elucidated. The aim of this study is to investigate the effect of scaffold struts on jailed SBs as assessed by 3-dimensional (3D) optical coherence tomography (OCT) after implantation of DREAMS 2G. We enrolled the patients who received a DREAMS 2G implantation and where OCT was performed at postprocedure and 12-month follow-up in the BIOSOLVE-II trial. The area of the ostium of jailed SBs and number of compartments divided by scaffold struts were assessed by cut-plane analysis using 3D OCT. A total of 24 patients with 61 jailed SBs were analyzed in this study. The number of compartments was significantly decreased (postprocedure; 1.98 +/- 0.84 vs 12 months; 1.10 +/- 0.30, p <0.001) during the 12 months. Since most of the struts disappeared, the ostium area was increased in 62% of jailed SBs at 12 months, however, not significantly different from postprocedure (postprocedure; 0.74 [0.34 to 1.46] mm<sup>2</sup> vs 12 months; 0.78 [0.41 to 1.68] mm<sup>2</sup>, p=0.055). The number of compartments created by scaffold struts and branching angle at postprocedure had no effect on the changes of SB ostium area. DREAMS 2G has a favorable absorption process in the jailed SBs up to 12 months and may be considered as an optional therapy for treating lesions that involve SBs.
English
*Absorbable Implants
*Coronary Artery Disease/su [Surgery]
*Coronary Vessels/dg [Diagnostic Imaging]
*Drug-Eluting Stents
*Imaging, Three-Dimensional/mt [Methods]
*Percutaneous Coronary Intervention/mt [Methods]
*Tomography, Optical Coherence/mt [Methods]
Aged
Coronary Artery Disease/di [Diagnosis]
Coronary Vessels/su [Surgery]
Female
Follow-Up Studies
Humans
Male
Prospective Studies
Prosthesis Design
Reproducibility of Results
Tissue Scaffolds
Treatment Outcome
MedStar Heart & Vascular Institute
MedStar Washington Hospital Center
Journal Article
Garcia-Garcia, Hector M
Hideo-Kajita, Alexandre
Kuku, Kayode
Ozaki, Yuichi
Waksman, Ron
Abizaid A, Christiansen EH, Escaned J, Garcia-Garcia HM, Haude M, Hideo-Kajita A, Ince H, Kuku KO, Lemos PA, Ozaki Y, Tolg R, von Birgelen C, Waksman R, Wijns W
https://dx.doi.org/10.1016/j.amjcard.2018.12.029
https://dx.doi.org/10.1016/j.amjcard.2018.12.029
ART
Article
0
0
0
0
Article
authcat
authcat
2019-03-14
0
30683424
30683424
2019-03-14
2019-03-14
ART
4109
4109