TY  - BOOK
AU  - Garcia-Garcia, Hector M
AU  - Hideo-Kajita, Alexandre
AU  - Kuku, Kayode
AU  - Ozaki, Yuichi
AU  - Waksman, Ron
TI  - Serial 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side-Branch by Second-Generation Drug-Eluting Absorbable Metal Scaffold (from the BIOSOLVE-II Trial)
SN  - 0002-9149
PY  - 2019///
KW  - *Absorbable Implants
KW  - *Coronary Artery Disease/su [Surgery]
KW  - *Coronary Vessels/dg [Diagnostic Imaging]
KW  - *Drug-Eluting Stents
KW  - *Imaging, Three-Dimensional/mt [Methods]
KW  - *Percutaneous Coronary Intervention/mt [Methods]
KW  - *Tomography, Optical Coherence/mt [Methods]
KW  - Aged
KW  - Coronary Artery Disease/di [Diagnosis]
KW  - Coronary Vessels/su [Surgery]
KW  - Female
KW  - Follow-Up Studies
KW  - Humans
KW  - Male
KW  - Prospective Studies
KW  - Prosthesis Design
KW  - Reproducibility of Results
KW  - Tissue Scaffolds
KW  - Treatment Outcome
KW  - MedStar Heart & Vascular Institute
KW  - MedStar Washington Hospital Center
KW  - Journal Article
N1  - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
N2  - Copyright (c) 2019. Published by Elsevier Inc; Second-generation drug-eluting absorbable metal scaffold (DREAMS 2G) is used for treating coronary lesions. However, the natural history of the jailed side-branch (SB) after DREAMS 2G implantation remains to be elucidated. The aim of this study is to investigate the effect of scaffold struts on jailed SBs as assessed by 3-dimensional (3D) optical coherence tomography (OCT) after implantation of DREAMS 2G. We enrolled the patients who received a DREAMS 2G implantation and where OCT was performed at postprocedure and 12-month follow-up in the BIOSOLVE-II trial. The area of the ostium of jailed SBs and number of compartments divided by scaffold struts were assessed by cut-plane analysis using 3D OCT. A total of 24 patients with 61 jailed SBs were analyzed in this study. The number of compartments was significantly decreased (postprocedure; 1.98 +/- 0.84 vs 12 months; 1.10 +/- 0.30, p <0.001) during the 12 months. Since most of the struts disappeared, the ostium area was increased in 62% of jailed SBs at 12 months, however, not significantly different from postprocedure (postprocedure; 0.74 [0.34 to 1.46] mm<sup>2</sup> vs 12 months; 0.78 [0.41 to 1.68] mm<sup>2</sup>, p=0.055). The number of compartments created by scaffold struts and branching angle at postprocedure had no effect on the changes of SB ostium area. DREAMS 2G has a favorable absorption process in the jailed SBs up to 12 months and may be considered as an optional therapy for treating lesions that involve SBs
UR  - https://dx.doi.org/10.1016/j.amjcard.2018.12.029
ER  -