04100nam a22006497a 4500008004200000022001400042024004000056024003200096040002000128099001300148245017700161251006600338252004800404252003100452253003900483260000900522260001100531265001700542266001500559268004900574501010900623520005100732520150000783546001202283650002502295650004202320650004602362650002502408650004502433650005302478650004802531650000902579650004302588650003402631650001102665650002202676650001102698650000902709650002402718650002202742650003102764650002102795650002202816651003902838651003902877657002002916700002802936700002802964700001702992700001803009700001703027790016503044856010303209942001703312952010603329999001503435190314s20192019 xxu||||| |||| 00| 0 eng d a0002-9149 a10.1016/j.amjcard.2018.12.029 [doi] aS0002-9149(19)30032-3 [pii] aOvid MEDLINE(R) a30683424 aSerial 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side-Branch by Second-Generation Drug-Eluting Absorbable Metal Scaffold (from the BIOSOLVE-II Trial). aAmerican Journal of Cardiology. 123(7):1044-1051, 2019 04 01. aAm J Cardiol. 123(7):1044-1051, 2019 04 01. zAm J Cardiol. 2019 Jan 04 aThe American journal of cardiology c2019 fFY2019 saheadofprint d2019-03-14 aAmerican Journal of Cardiology. 2019 Jan 04 aAvailable online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 aCopyright (c) 2019. Published by Elsevier Inc. aSecond-generation drug-eluting absorbable metal scaffold (DREAMS 2G) is used for treating coronary lesions. However, the natural history of the jailed side-branch (SB) after DREAMS 2G implantation remains to be elucidated. The aim of this study is to investigate the effect of scaffold struts on jailed SBs as assessed by 3-dimensional (3D) optical coherence tomography (OCT) after implantation of DREAMS 2G. We enrolled the patients who received a DREAMS 2G implantation and where OCT was performed at postprocedure and 12-month follow-up in the BIOSOLVE-II trial. The area of the ostium of jailed SBs and number of compartments divided by scaffold struts were assessed by cut-plane analysis using 3D OCT. A total of 24 patients with 61 jailed SBs were analyzed in this study. The number of compartments was significantly decreased (postprocedure; 1.98 +/- 0.84 vs 12 months; 1.10 +/- 0.30, p <0.001) during the 12 months. Since most of the struts disappeared, the ostium area was increased in 62% of jailed SBs at 12 months, however, not significantly different from postprocedure (postprocedure; 0.74 [0.34 to 1.46] mm2 vs 12 months; 0.78 [0.41 to 1.68] mm2, p=0.055). The number of compartments created by scaffold struts and branching angle at postprocedure had no effect on the changes of SB ostium area. DREAMS 2G has a favorable absorption process in the jailed SBs up to 12 months and may be considered as an optional therapy for treating lesions that involve SBs. aEnglish a*Absorbable Implants a*Coronary Artery Disease/su [Surgery] a*Coronary Vessels/dg [Diagnostic Imaging] a*Drug-Eluting Stents a*Imaging, Three-Dimensional/mt [Methods] a*Percutaneous Coronary Intervention/mt [Methods] a*Tomography, Optical Coherence/mt [Methods] aAged aCoronary Artery Disease/di [Diagnosis] aCoronary Vessels/su [Surgery] aFemale aFollow-Up Studies aHumans aMale aProspective Studies aProsthesis Design aReproducibility of Results aTissue Scaffolds aTreatment Outcome aMedStar Heart & Vascular Institute aMedStar Washington Hospital Center aJournal Article aGarcia-Garcia, Hector M aHideo-Kajita, Alexandre aKuku, Kayode aOzaki, Yuichi aWaksman, Ron aAbizaid A, Christiansen EH, Escaned J, Garcia-Garcia HM, Haude M, Hideo-Kajita A, Ince H, Kuku KO, Lemos PA, Ozaki Y, Tolg R, von Birgelen C, Waksman R, Wijns W uhttps://dx.doi.org/10.1016/j.amjcard.2018.12.029zhttps://dx.doi.org/10.1016/j.amjcard.2018.12.029 cARTdArticle 001040708Articleaauthcatbauthcatd2019-03-14l0o30683424p30683424r2019-03-14w2019-03-14yART c4109d4109