TY - BOOK AU - Chen, Yuefeng AU - Gajanana, Deepakraj AU - Iantorno, Micaela AU - Khalid, Nauman AU - Khan, Jaffar M AU - Kolm, Paul AU - Musallam, Anees AU - Rogers, Toby AU - Shlofmitz, Evan AU - Torguson, Rebecca AU - Waksman, Ron AU - Weintraub, William S TI - Racial Disparities in Clinical Characteristics and Outcomes of Women Undergoing Percutaneous Coronary Intervention SN - 1878-0938 PY - 2019/// KW - *African Americans KW - *Coronary Artery Disease/th [Therapy] KW - *European Continental Ancestry Group KW - *Health Status Disparities KW - *Healthcare Disparities/eh [Ethnology] KW - *Percutaneous Coronary Intervention KW - Aged KW - Aged, 80 and over KW - Coronary Artery Disease/di [Diagnosis] KW - Coronary Artery Disease/eh [Ethnology] KW - Coronary Artery Disease/mo [Mortality] KW - Databases, Factual KW - Female KW - Humans KW - Middle Aged KW - Percutaneous Coronary Intervention/ae [Adverse Effects] KW - Percutaneous Coronary Intervention/mo [Mortality] KW - Race Factors KW - Retrospective Studies KW - Risk Assessment KW - Risk Factors KW - Sex Factors KW - Treatment Outcome KW - United States/ep [Epidemiology] KW - MedStar Heart & Vascular Institute KW - Journal Article N1 - Available in print through MWHC library: 2002 - present N2 - BACKGROUND/PURPOSE: Women are underrepresented in cardiovascular clinical studies. Black women have a higher ischemic heart disease mortality risk than their white counterparts. However, there exist limited outcome data comparing black women and white women after percutaneous coronary intervention (PCI). The aim of this retrospective analysis was to evaluate for racial disparities in 1-year major adverse cardiovascular events (MACE) in women undergoing PCI; CONCLUSIONS: In this large cohort of women with coronary artery disease undergoing PCI, we observed racial disparities primarily in baseline characteristics indicative of need for interventions to achieve early diagnosis and better prevention in black women. Future directions should include efforts to identify and better characterize the factors underlying and contributing to cardiovascular outcomes in women after PCI; METHODS/MATERIALS: Within our PCI database, we identified 4776 female patients who underwent PCI between 2003 and 2016. Of those, 1916 were black and 2860 were white. Endpoints included MACE, death, myocardial infarction, target vessel revascularization (TVR) and stent thrombosis (ST) at 30days and 1year. A proportional Cox hazard model analysis was performed to assess outcomes after adjustment for confounding factors; RESULTS: Black women presented at a younger age and had a significantly higher prevalence of risk factors. Periprocedural and in-hospital outcomes were similar in the 2 groups. At 30days and 1year, the rates of myocardial infarction, TVR and ST were significantly higher in black women. After adjustment for baseline differences, only ST appears to be more likely to occur in black women than in white women; SUMMARY: In this real-world analysis from a large cohort of women with coronary artery disease undergoing percutaneous coronary intervention at a US tertiary-care center, racial disparities were observed, especially in baseline characteristics, indicating late presentation. Copyright (c) 2019 Elsevier Inc. All rights reserved UR - https://dx.doi.org/10.1016/j.carrev.2019.09.020 ER -