TY - BOOK AU - Abousayed, Mostafa M TI - Orthopaedic Manifestations of Melanoma and Their Management. [Review] SN - 1067-151X PY - 2020/// KW - *Bone Neoplasms/sc [Secondary] KW - *Melanoma/sc [Secondary] KW - *Muscle Neoplasms/sc [Secondary] KW - *Orthopedics KW - *Skin Neoplasms/pa [Pathology] KW - *Skin/pa [Pathology] KW - Biopsy KW - Bone Neoplasms/di [Diagnosis] KW - Bone Neoplasms/pa [Pathology] KW - Bone Neoplasms/th [Therapy] KW - Diagnosis, Differential KW - Humans KW - Melanoma/di [Diagnosis] KW - Melanoma/pa [Pathology] KW - Melanoma/th [Therapy] KW - Muscle Neoplasms/di [Diagnosis] KW - Muscle Neoplasms/pa [Pathology] KW - Muscle Neoplasms/th [Therapy] KW - Orthopedic Surgeons KW - Physical Examination KW - Prognosis KW - Skin Neoplasms/di [Diagnosis] KW - Skin Neoplasms/th [Therapy] KW - MedStar Union Memorial Hospital KW - Orthopaedic Surgery KW - Journal Article N1 - Available online from MWHC library: Oct 1993 - present, Available in print through MWHC library: 1999 - present N2 - Melanoma is an aggressive form of skin cancer associated with significant morbidity and mortality. Although commonly seen in dermatologist clinics, orthopaedic surgeons must be aware of these lesions in various ways. The five common musculoskeletal manifestations of melanoma will be discussed as well as the epidemiology, pathogenesis, diagnosis, staging, treatment, and prognosis of melanoma. With an index of suspicion and awareness of melanoma, a thorough history and detailed physical examination are critical in establishing a diagnosis. An adequately performed biopsy will confirm the diagnosis and assist in determining prognosis. As ambassadors of health for the musculoskeletal system, orthopaedic surgeons may be the first practitioners to encounter a pigmented skin lesion. Acral pigmented lesions should prompt a concern for melanoma with appropriate subsequent steps for management to follow. Finally, it is important for every orthopaedic surgeon to consider disseminated melanoma in the differential diagnosis of a skeletal metastasis, a deep soft-tissue mass, or lymphadenopathy in a patient with a previous history of a melanotic lesion UR - https://dx.doi.org/10.5435/JAAOS-D-18-00757 ER -