TY - BOOK AU - Khan, Jaffar M AU - Rogers, Toby TI - First-in-human transcatheter pledget-assisted suture tricuspid annuloplasty for severe tricuspid insufficiency SN - 1522-1946 PY - 2021/// KW - *Cardiac Valve Annuloplasty KW - *Heart Valve Prosthesis Implantation KW - *Tricuspid Valve Insufficiency KW - Aged, 80 and over KW - Cardiac Valve Annuloplasty/ae [Adverse Effects] KW - Heart Valve Prosthesis Implantation/ae [Adverse Effects] KW - Humans KW - Male KW - Mitral Valve KW - Sutures KW - Treatment Outcome KW - Tricuspid Valve Insufficiency/dg [Diagnostic Imaging] KW - Tricuspid Valve Insufficiency/su [Surgery] KW - Tricuspid Valve/dg [Diagnostic Imaging] KW - Tricuspid Valve/su [Surgery] KW - MedStar Heart & Vascular Institute KW - Journal Article N1 - Available online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006 N2 - BACKGROUND: Tricuspid valve regurgitation is a common malignant disease with no commercially available transcatheter therapy. PASTA is a "percutaneous surgical" procedure using pledgeted sutures to create a double-orifice tricuspid valve; CONCLUSIONS: The anatomy of a double-orifice valve can eliminate TR but a better solution is required to avoid excessive suture tension on annular tissue. Copyright Published 2020. This article is a U.S. Government work and is in the public domain in the USA; METHODS: An 83-year-old man had end-stage TR caused by a defibrillator lead. He consented to undergo PASTA on a compassionate basis. A double-orifice valve was created with pledgeted sutures from percutaneous right ventricular apical access; OBJECTIVES: We report the first pledget-assisted suture tricuspid annuloplasty (PASTA) in a patient with torrential tricuspid regurgitation (TR); RESULTS: TR was reduced from torrential to trace. The vena contracta reduced to from 23 to 1 mm and annular area reduced from 1817 to 782 mm2 . However, the annulus dehisced and required closure with a percutaneous nitinol plug. The patient was discharged home and was alive 6 months later but with persistent symptoms UR - https://dx.doi.org/10.1002/ccd.28955 ER -