TY  - BOOK
AU  - Armonda, Rocco A
AU  - Aulisi, Edward
AU  - Chang, Jason J
AU  - Corbin, Maite J
AU  - Desale, Sameer
AU  - Felbaum, Daniel R
AU  - Liu, Ai-Hsi
AU  - Mai, Jeffrey C
AU  - Triano, Matthew
TI  - Transcranial Doppler velocity and associations with delayed cerebral ischemia in aneurysmal subarachnoid Hemorrhage
SN  - 0022-510X
PY  - 2020///
KW  - IN PROCESS -- NOT YET INDEXED
KW  - MedStar Heart & Vascular Institute
KW  - MedStar Washington Hospital Center
KW  - Neurosurgery
KW  - Radiology
KW  - Surgery/Surgical Critical Care
KW  - Journal Article
N2  - BACKGROUND AND PURPOSE: We evaluated optimal transcranial Doppler (TCD) measures for predicting delayed cerebral ischemia (DCI) after aneurysmal  subarachnoid hemorrhage (aSAH); CONCLUSIONS: We found that relative increases in TCD velocities in the MCAs during the first 7 days (with a threshold increase of 53.4 cm/s from days  2 to 7) after aSAH admission were independently associated with DCI. This association requires independent confirmation. Copyright (c) 2020 Elsevier B.V.  All rights reserved; MATERIAL AND METHODS: Consecutive patients with aSAH and daily middle cerebral artery (MCA) TCD recordings were retrospectively analyzed. Change in  TCD velocity was obtained by creating a smoothing curve. Change in TCD velocity was determined with a linear regression model that confirmed greatest change  in velocity associated with DCI occurred at days 2-7. Multivariate logistic regression analysis was then completed; RESULTS: 95 patients were evaluated. Increase in TCD velocity at days 2-7 proved to be the best predictor for DCI with an optimal cutoff of 8.9  cm/s/day (p = .019) and AUC 0.651. Multivariate logistic regression analysis using DCI as outcome showed that poor admission Hunt-Hess scores (OR 5.02,  95%CI 1.22-22.67, p = .028) and increases in TCD velocity (OR 5.32, 95%CI 1.41-23.33, p = .018) were independently associated with DCI
UR  - https://dx.doi.org/10.1016/j.jns.2020.116934
ER  -