TY  - BOOK
AU  - Chezar-Azerrad, Chava
AU  - Dan, Kazuhiro
AU  - Garcia-Garcia, Hector M
AU  - Kuku, Kayode
AU  - Ozaki, Yuichi
AU  - Singh, Manavotam
AU  - Waksman, Ron
TI  - Near-Infrared Spectroscopy Intravascular Ultrasound Imaging: State of the Art. [Review]
SN  - 2297-055X
PY  - 2020///
KW  - IN PROCESS -- NOT YET INDEXED
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
KW  - Review
N2  - Acute coronary syndromes (ACS) secondary to coronary vessel plaques represent a major cause of cardiovascular morbidity and mortality worldwide. Advancements in imaging technology over the last 3 decades have continuously enabled the study of coronary plaques via invasive imaging methods like intravascular ultrasound (IVUS) and optical coherence tomography (OCT). The introduction of near-infrared spectroscopy (NIRS) as a modality that could detect the lipid (cholesterol) content of atherosclerotic plaques in the early nineties, opened the potential of studying "vulnerable" or rupture-prone, lipid-rich coronary plaques in ACS patients. Most recently, the ability of NIRS-IVUS to identify patients at risk of future adverse events was shown in a prospective multicenter trial, the Lipid-Rich-plaque Study. Intracoronary NIRS-IVUS imaging offers a unique method of coronary lipid-plaque characterization and could become a valuable clinical diagnostic and treatment monitoring tool. Copyright (c) 2020 Kuku, Singh, Ozaki, Dan, Chezar-Azerrad, Waksman and Garcia-Garcia
UR  - https://dx.doi.org/10.3389/fcvm.2020.00107
ER  -