TY - BOOK AU - Barriola, Rodrigo AU - Ben-Dor, Itsik AU - Beyene, Solomon AU - Case, Brian C AU - Chezar-Azerrad, Chava AU - Dan, Kazuhiro AU - Forrestal, Brian J AU - Garcia-Garcia, Hector M AU - Hashim, Hayder AU - Kuku, Kayode AU - Medranda, Giorgio A AU - Melaku, Gebremedhin AU - Shlofmitz, Evan AU - Waksman, Ron AU - Yerasi, Charan TI - Optical Coherence Tomography based treatment approach for patients with Acute Coronary Syndrome. [Review] SN - 1477-9072 PY - 2021/// KW - *Acute Coronary Syndrome/th [Therapy] KW - *Plaque, Atherosclerotic/th [Therapy] KW - *Tomography, Optical Coherence/mt [Methods] KW - Coronary Angiography KW - Humans KW - Percutaneous Coronary Intervention KW - Thrombosis/et [Etiology] KW - MedStar Heart & Vascular Institute KW - Journal Article N2 - AREAS COVERED: In this review, we outline the underlying causes of acute coronary syndrome (ACS) as evaluated by optical coherence tomography (OCT). We report both the definitions of each mechanism and its frequency as reported in the literature to date. Finally, we present an algorithm based on the findings in the review that gives an outlined approach to perform intervention on ACS patients; EXPERT OPINION: Although the most common and most accepted intervention in ACS cases is stent implantation, data suggest a stentless approach in cases of plaque erosion, which generally occurs in younger patients presenting with an acute coronary syndrome that have TIMI flow of 2/3 and either a small or large burden of thrombus and underlying stenosis of less than 50% UR - https://dx.doi.org/10.1080/14779072.2021.1857732 ER -