TY - BOOK AU - Garcia-Garcia, Hector M AU - Varghese, Jobin TI - Impact of migraine headaches on stress induced 'Takotsubo' cardiomyopathy SN - 1878-0938 PY - 2022/// KW - IN PROCESS -- NOT YET INDEXED KW - MedStar Heart & Vascular Institute KW - MedStar Washington Hospital Center KW - Internal Medicine Residency Joseph KW - Journal Article N2 - CONCLUSIONS: TCM patients with migraines were found to have a better outcome and mortality. They had significantly fewer complications (cardiac arrest, heart failure exacerbation, intubation, acute kidney injury). Copyright © 2022 Elsevier Inc. All rights reserved; INTRODUCTION: Takotsubo cardiomyopathy (TCM) is an acute left ventricular dysfunction, typically due to a neuro-cardiogenic mechanism. Although many stressors can precipitate TCM, the role of migraines in hospitalized TCM patients has not been studied. Our objective is to describe the in-hospital outcomes of TCM in patients with a concurrent diagnosis of migraines; METHODS: We conducted a US-wide analysis of TCM hospitalizations from 2013 to 2017 by querying the National Inpatient Sample database for the International Classification of Diseases-ninth Revision. Patients admitted with a principal diagnosis of TCM with a history of migraines were identified using the ICD-10 codes. TCM patients with migraines were then compared to TCM patients without migraines regarding mortality and acute inpatient complications (intubation, cardiac arrest, heart failure exacerbation, acute kidney injury). A logistic regression model was constructed to account for potential confounders; RESULTS: A total of 172,025 TCM patients were identified. Of those patients, 3610 suffered from migraines. TCM patients with a diagnosis of migraine were associated with a lower odds for mortality (OR: 0.388; [0.311-0.485]; p < 0.001) and acute complications (OR: 0.511 [0.471-0.554]; p < 0.001) compared to those without migraines. After adjusting for confounders, the adjusted odds ratio for mortality was 0.622; [0.495-0.782]; p < 0.001, and acute complications were 0.563 [0.519-0.611]; p < 0.001 UR - https://dx.doi.org/10.1016/j.carrev.2022.03.005 ER -