TY  - BOOK
AU  - Orr, Lindsey
TI  - Comparison of the GenCut Core Biopsy System to Transbronchial Biopsy Forceps for Flexible Bronchoscopic Lung Biopsy
SN  - 1948-8270
PY  - 2022///
KW  - *Bronchoscopy
KW  - *Lung Neoplasms
KW  - Biopsy, Fine-Needle
KW  - Biopsy, Large-Core Needle
KW  - Bronchoscopy/mt [Methods]
KW  - Humans
KW  - Lung Neoplasms/di [Diagnosis]
KW  - Lung Neoplasms/pa [Pathology]
KW  - Lung/pa [Pathology]
KW  - Surgical Instruments
KW  - MedStar Georgetown University Hospital/MedStar Washington Hospital Center
KW  - Pulmonary Disease & Critical Care Medicine Fellowship
KW  - Journal Article
KW  - Observational Study
N2  - BACKGROUND: Pulmonary nodules are increasingly detected on screening and routine chest imaging, leading to an increase in diagnostic procedures. Bronchoscopy with transbronchial biopsy (TBBx) is the most common diagnostic modality, with diagnostic yield between 43% and 86%, largely dependent on the use of navigational modalities. In 2015 a new biopsy tool by Medtronic, the GenCut core biopsy system [GenCut transbronchial needle aspiration (TBNA)], was developed with the intention of improving yield in lung nodule biopsies. Our goal was to determine the efficacy of this new device when used in addition to TBBx; CONCLUSION: The diagnostic yield is improved by using the GenCut core biopsy system in addition to traditional TBBx forceps when performing bronchoscopy for pulmonary nodules, without an increase in complications. These biopsy methods should be used in tandem for the greatest yield. Copyright ♭ 2021 Wolters Kluwer Health, Inc. All rights reserved; PATIENTS AND METHODS: This is a prospective observational study of 324 consecutive bronchoscopic lung biopsies in which both TBBx and GenCut TBNA were performed on the same lesion. We recorded patient and nodule characteristics, along with the bronchoscopic modalities used. The primary outcome was the diagnostic yield with the addition of the GenCut TBNA, and the key secondary outcome was the complication rate; RESULTS: Of the 324 nodule biopsies analyzed, 164 (50.6%) were diagnostic via TBBx or GenCut TBNA. In all, 97 (59%) were positive in both TBBx and GenCut TBNA, 43 (26.2%) were positive only in TBBx, and 24 (14.6%) were positive only in GenCut TBNA. Overall, the addition of the GenCut TBNA increased the diagnostic yield by 7.4% (P<0.01). There were 7 complications: 5 pneumothoraxes and 2 episodes of bleeding
UR  - https://dx.doi.org/10.1097/LBR.0000000000000803
ER  -