TY - BOOK AU - Cook, Helene AU - Steinberg, John S AU - Tefera, Eshetu TI - Risks Factors Associated With Major Lower Extremity Amputation After Vertical Contour Calcanectomy PY - 2022/// KW - IN PROCESS -- NOT YET INDEXED KW - MedStar Health Research Institute KW - MedStar Washington Hospital Center KW - Podiatric Surgery Residency KW - Surgery/Podiatric Surgery KW - Journal Article N1 - Available online through MWHC library: 2003 - present, Available in print through MWHC library:1999-2007 N2 - The primary aim of the study is to determine risks for major lower extremity amputation after undergoing Vertical Contour Calcanectomy. Subanalysis was performed comparing patients who underwent Vertical Contour Calcanectomy who were fully ambulatory to those who were partially or nonambulatory postoperatively. Within the cohort of 63 patients included in the Vertical Contour Calcanectomy 85.71% (54/63) of patients had diabetes mellitus, 53.97% (34/63) had peripheral arterial disease, and 19.05% (12/63) had Charcot Neuroarthropathy. Multivariate logistic regression, found that (1) patients that underwent primary closure at the time of the Vertical Contour Calcanectomy, were 79.9% more likely (odds ratio [OR] 0.20; 95% confidence interval [CI] 0.04-0.96) to have limb salvage and that (2) female patients were 85.4% less likely compared to male patients (OR 0.15; 95% CI 0.02-0.99) to undergo major lower extremity amputation. Patients with coronary artery disease were 5.2 times more likely (OR 5.18; 95% CI 1.120-23.94) and patients that were nonambulatory preoperatively, were 10.3 times more likely (OR 10.28; 95% CI 1.60-66.26), to be partially or nonambulatory after Vertical Contour Calcanectomy. Primary closure at time of Vertical Contour Calcanectomy significantly decreases the risk of major lower extremity amputation, and diminished preoperative ambulatory status as well as coronary artery disease makes it less likely that patients return to full ambulation after Vertical Contour Calcanectomy. Copyright (c) 2022 the American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved UR - https://dx.doi.org/10.1053/j.jfas.2022.01.013 ER -