Asynchronous Bilateral Achilles Tendon Rupture with Selective Androgen Receptor Modulators: A Case Report.

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Citation: Jbjs Case Connector. 11(2), 2021 04 09.PMID: 33835995Institution: MedStar Union Memorial HospitalDepartment: Orthopaedic Surgery | Orthopaedic Surgery ResidencyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Achilles Tendon | *Ankle Injuries | *Tendon Injuries | Achilles Tendon/su [Surgery] | Adult | Humans | Male | Receptors, Androgen | Rupture/ci [Chemically Induced] | Rupture/su [Surgery] | Tendon Injuries/ci [Chemically Induced] | Tendon Injuries/su [Surgery]Year: 2021ISSN:
  • 2160-3251
Name of journal: JBJS case connectorAbstract: CASE: A 36-year-old male competitive powerlifter sustained asynchronous bilateral Achilles tendon ruptures after using 2 types of selective androgen receptor modulators (SARMs). Both tendon ruptures occurred near the myotendinous junction and were treated with open surgical repair and an initial period of immobilization followed by progressive weightbearing and rehabilitation; no postoperative complications were observed.CONCLUSION: Previous studies have reported that anabolic androgenic steroids have a deleterious impact on tendon structure and function. This case suggests that SARM compounds may also predispose users to Achilles tendon rupture. Copyright (c) 2021 by The Journal of Bone and Joint Surgery, Incorporated.All authors: Duvall GT, Gould HP, Hammond JW, Hawken JBOriginally published: Jbjs Case Connector. 11(2), 2021 04 09.Fiscal year: FY2021Digital Object Identifier: ORCID: Date added to catalog: 2021-06-07
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Journal Article MedStar Authors Catalog Article 33835995 Available 33835995

CASE: A 36-year-old male competitive powerlifter sustained asynchronous bilateral Achilles tendon ruptures after using 2 types of selective androgen receptor modulators (SARMs). Both tendon ruptures occurred near the myotendinous junction and were treated with open surgical repair and an initial period of immobilization followed by progressive weightbearing and rehabilitation; no postoperative complications were observed.

CONCLUSION: Previous studies have reported that anabolic androgenic steroids have a deleterious impact on tendon structure and function. This case suggests that SARM compounds may also predispose users to Achilles tendon rupture. Copyright (c) 2021 by The Journal of Bone and Joint Surgery, Incorporated.

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