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Pulmonary Arterial Hypertension: Diagnosis and Treatment. [Review]

MedStar author(s):

Citation: Cardiology Clinics. 34(3):375-89, 2016 AugPMID: 27443135Institution: MedStar Heart & Vascular InstituteIN - Barnett, Christopher F. Medstar Heart and Vascular Institute, 110 Irving Street Northwest Washington, DC 20010, USA; Critical Care Medicine Department, National Institutes of Health, 10 Center Drive, Room 2C145, Bethesda, MD 20892, USA.IN - Alvarez, Paulino. Department of Cardiology, Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, 6550 Fannin Street, Smith Tower, Suite 1901, Houston, TX 77030, USA.IN - Park, Myung H. Division of Heart Failure and Transplant, Department of Cardiology, Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, 6550 Fannin Street, Smith Tower, Suite 1901, Houston, TX 77030, USA. Electronic address: [email protected].Form of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Antihypertensive Agents/tu [Therapeutic Use] | *Diagnostic Imaging/mt [Methods] | *Heart Ventricles/dg [Diagnostic Imaging] | *Hypertension, Pulmonary/di [Diagnosis] | Cardiac Catheterization | Echocardiography | Electrocardiography | Heart Ventricles/pp [Physiopathology] | Humans | Hypertension, Pulmonary/pp [Physiopathology] | Hypertension, Pulmonary/th [Therapy] | Magnetic Resonance Imaging, Cine | Radiography, ThoracicYear: 2016 Local holdings: Available online from MWHC library: 1996 - present, Available in print through MWHC library: August 1998 - February 2004ISSN:

0733-8651

Name of journal: Cardiology clinicsAbstract: Copyright © 2016 Elsevier Inc. All rights reserved.Pulmonary arterial hypertension (PAH) is a specific, rare disease characterized by a well-described pattern of pulmonary vascular remodeling. The elevated pulmonary artery pressure in PAH results in increased right ventricular afterload, which, if untreated, leads rapidly to right ventricular failure and death. Recent marked expansion in knowledge about PAH has resulted in the development of effective therapies that improve quality of life and survival. However, delays in diagnosis and suboptimal treatment remain significant barriers to achieving optimal patient outcomes. Continued success in raising PAH awareness, earlier diagnosis, and the availability of new therapies mean a promising future for PAH patients. All authors: Alvarez P, Barnett CF, Park MHFiscal year: FY2017Digital Object Identifier:

https://dx.doi.org/10.1016/j.ccl.2016.04.006

Date added to catalog: 2017-05-06

Holdings ( 1 )
Title notes ( 4 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	27443135	Available		27443135

Available online from MWHC library: 1996 - present, Available in print through MWHC library: August 1998 - February 2004

Pulmonary arterial hypertension (PAH) is a specific, rare disease characterized by a well-described pattern of pulmonary vascular remodeling. The elevated pulmonary artery pressure in PAH results in increased right ventricular afterload, which, if untreated, leads rapidly to right ventricular failure and death. Recent marked expansion in knowledge about PAH has resulted in the development of effective therapies that improve quality of life and survival. However, delays in diagnosis and suboptimal treatment remain significant barriers to achieving optimal patient outcomes. Continued success in raising PAH awareness, earlier diagnosis, and the availability of new therapies mean a promising future for PAH patients.

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