Preventing clostridium difficile infection in the intensive care unit. [Review]

MedStar author(s):
Citation: Critical Care Clinics. 29(1):11-8, 2013 Jan.PMID: 23182524Institution: MedStar Washington Hospital CenterDepartment: Medicine/Pulmonary-Critical CareForm of publication: Journal ArticleMedline article type(s): Journal Article | Research Support, Non-U.S. Gov't | ReviewSubject headings: *Anti-Bacterial Agents/ae [Adverse Effects] | *Clostridium Infections/pc [Prevention & Control] | *Cross Infection/pc [Prevention & Control] | *Intensive Care Units/st [Standards] | Anti-Bacterial Agents/st [Standards] | Anti-Bacterial Agents/tu [Therapeutic Use] | Clostridium difficile/cl [Classification] | Clostridium difficile/de [Drug Effects] | Clostridium difficile/ge [Genetics] | Clostridium difficile/py [Pathogenicity] | Clostridium Infections/dt [Drug Therapy] | Clostridium Infections/ep [Epidemiology] | Costs and Cost Analysis | Critical Illness | Cross Infection/mi [Microbiology] | Diarrhea/ci [Chemically Induced] | Diarrhea/mi [Microbiology] | Disease Outbreaks | Disinfection/mt [Methods] | Disinfection/st [Standards] | Drug Resistance, Multiple, Bacterial/de [Drug Effects] | Hand Hygiene/mt [Methods] | Hand Hygiene/st [Standards] | Humans | Infection Control/mt [Methods] | Infection Control/st [Standards] | Intensive Care Units/og [Organization & Administration] | Prevalence | Probiotics/st [Standards] | Probiotics/tu [Therapeutic Use] | Risk Factors | Virulence/de [Drug Effects] | Virulence/ge [Genetics]Year: 2013Local holdings: Available online from MWHC library: 1996 - presentISSN:
  • 0749-0704
Name of journal: Critical care clinicsAbstract: Clostridium difficile is a formidable problem in the twenty-first century. Because of injudicious use of antibiotics, the emergence of the hypervirulent epidemic strain of this organism has been difficult to contain. The NAP1/BI/027 strain causes more-severe disease than other widely prevalent strains and affects patients who were not traditionally thought to be at risk for Clostridium difficile infection. Critically ill patients remain at high risk for this pathogen, and preventive measures, such as meticulous contact precautions, hand hygiene, environmental disinfection, and, most importantly, antibiotic stewardship, are the cornerstones of mitigation in the intensive care unit. Copyright 2013 Elsevier Inc. All rights reserved.All authors: Shorr AF, Zilberberg MDFiscal year: FY2013Digital Object Identifier: Date added to catalog: 2013-09-17
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 23182524 Available 23182524

Available online from MWHC library: 1996 - present

Clostridium difficile is a formidable problem in the twenty-first century. Because of injudicious use of antibiotics, the emergence of the hypervirulent epidemic strain of this organism has been difficult to contain. The NAP1/BI/027 strain causes more-severe disease than other widely prevalent strains and affects patients who were not traditionally thought to be at risk for Clostridium difficile infection. Critically ill patients remain at high risk for this pathogen, and preventive measures, such as meticulous contact precautions, hand hygiene, environmental disinfection, and, most importantly, antibiotic stewardship, are the cornerstones of mitigation in the intensive care unit. Copyright 2013 Elsevier Inc. All rights reserved.

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