The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol.
Citation: Stroke. 44(10):e120-5, 2013 Oct.PMID: 24021679Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal Article | Multicenter Study | Randomized Controlled Trial | Research Support, N.I.H., ExtramuralSubject headings: *African Americans | *Cerebral Hemorrhage | *Databases, Factual | *European Continental Ancestry Group | *Hispanic Americans | Adolescent | Adult | Aged | Aged, 80 and over | Case-Control Studies | Cerebral Hemorrhage/eh [Ethnology] | Cerebral Hemorrhage/ep [Epidemiology] | Cerebral Hemorrhage/ra [Radiography] | Cerebral Hemorrhage/th [Therapy] | Female | Humans | Male | Middle Aged | Prospective Studies | Sex Factors | Tomography, X-Ray ComputedLocal holdings: Available online from MWHC library: 1970 - present, Available in print through MWHC library: 1999 - 2006ISSN:- 0039-2499
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
---|---|---|---|---|---|---|
Journal Article | MedStar Authors Catalog | Article | Available | 24021679 |
Available online from MWHC library: 1970 - present, Available in print through MWHC library: 1999 - 2006
BACKGROUND AND PURPOSE: Epidemiological studies of intracerebral hemorrhage (ICH) have consistently demonstrated variation in incidence, location, age at presentation, and outcomes among non-Hispanic white, black, and Hispanic populations. We report here the design and methods for this large, prospective, multi-center case-control study of ICH.
CONCLUSIONS: The ERICH study is a large, case-control study of ICH with particular emphasis on recruitment of minority populations for the identification of genetic and epidemiological risk factors for ICH and outcomes after ICH.
METHODS: The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a multi-center, prospective case-control study of ICH. Cases are identified by hot-pursuit and enrolled using standard phenotype and risk factor information and include neuroimaging and blood sample collection. Controls are centrally identified by random digit dialing to match cases by age (+5 years), race, ethnicity, sex, and metropolitan region.
RESULTS: As of March 22, 2013, 1655 cases of ICH had been recruited into the study, which is 101.5% of the target for that date, and 851 controls had been recruited, which is 67.2% of the target for that date (1267 controls) for a total of 2506 subjects, which is 86.5% of the target for that date (2897 subjects). Of the 1655 cases enrolled, 1640 cases had the case interview entered into the database, of which 628 (38%) were non-Hispanic black, 458 (28%) were non-Hispanic white, and 554 (34%) were Hispanic. Of the 1197 cases with imaging submitted, 876 (73.2%) had a 24 hour follow-up CT available. In addition to CT imaging, 607 cases have had MRI evaluation.
English