Characteristics and management of patients with acute coronary syndrome and normal or non-significant coronary artery disease: results from Acute Coronary Syndrome Israeli Survey (ACSIS) 2004-2010.
Citation: Journal of Invasive Cardiology. 26(8):389-93, 2014 Aug.PMID: 25091099Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Acute Coronary Syndrome | *Coronary Artery Disease/pp [Physiopathology] | *Disease Management | Acute Coronary Syndrome/di [Diagnosis] | Acute Coronary Syndrome/et [Etiology] | Acute Coronary Syndrome/mo [Mortality] | Acute Coronary Syndrome/pp [Physiopathology] | Acute Coronary Syndrome/th [Therapy] | Age Factors | Aged | Coronary Angiography/mt [Methods] | Coronary Artery Disease/co [Complications] | Coronary Artery Disease/di [Diagnosis] | Female | Health Surveys | Hospital Mortality | Hospitalization/sn [Statistics & Numerical Data] | Humans | Israel/ep [Epidemiology] | Male | Middle Aged | Risk Factors | Sex FactorsYear: 2014Local holdings: Available online from MWHC library: 2001 - present, Available in print through MWHC library: 2003 - 2008ISSN:- 1042-3931
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
---|---|---|---|---|---|---|
Journal Article | MedStar Authors Catalog | Article | 25091099 | Available | 25091099 |
Available online from MWHC library: 2001 - present, Available in print through MWHC library: 2003 - 2008
BACKGROUND: An important subset of patients presenting with acute coronary syndrome (ACS) are found to have either normal coronaries (NCs) or non-obstructive coronary artery disease (NOCAD; lumen diameter narrowing <50%).
CONCLUSIONS: In a real-world practice of ACS, underutilization of evidence-based medications in patients with NC or NOCAD was observed. Nonetheless, its prognostic significance is still unknown and must be explored in larger patient cohorts.
METHODS: The Acute Coronary Syndrome Israeli Survey (ACSIS) database was utilized to compare the characteristics and therapeutic approach for patients who underwent angiography for ACS and had either NC (n = 84; 2%), NOCAD (n = 79; 2%), or obstructive coronary artery disease (OCAD; n = 3523; 96%).
OBJECTIVES: To explore the characteristics and management strategies in this population in a real-world setting.
RESULTS: Baseline characteristics were comparable, save for a younger age and a higher proportion of females in the NC group (P<.001 for both). Prior to admission, chronic anticoagulant therapy was more frequently used in the NC vs. the OCAD group (4.8% vs. 1.6%, respectively; P=.02). Recommended ACS evidence-based medications, both in-hospital and at discharge, were less frequently prescribed to patients with NC or NOCAD.
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