000			03447nam a22006017a 4500
008			160113s20122012 xxu||||| |||| 00| 0 eng d
022			_a1553-5592
040			_aOvid MEDLINE(R)
099			_a22042764
245			_aComparing the pulmonary embolism severity index and the prognosis in pulmonary embolism scores as risk stratification tools.
251			_aJournal of Hospital Medicine (Online). 7(1):22-7, 2012 Jan.
252			_aJ Hosp Med. 7(1):22-7, 2012 Jan.
253			_aJournal of hospital medicine
260			_c2012
260			_fFY2012
266			_d2016-01-13
501			_aAvailable in print through MWHC library: 2007 only
520			_aBACKGROUND: Multiple risk stratification scoring systems exist to forecast outcomes in patients with acute pulmonary embolism (PE).
520			_aCONCLUSIONS: The PREP score performed comparably to the PESI score for identifying PE patients at low risk for short-term and intermediate-term mortality.Copyright � 2011 Society of Hospital Medicine.
520			_aDESIGN: Retrospective observational cohort study.
520			_aINTERVENTION: The PESI and PREP scores were calculated.
520			_aMEASUREMENTS: Raw PESI scores were segregated into risk class (I-V) and then dichotomized into low (I-II) versus high (III-V) risk groups; the raw PREP scores were divided into low (0-7) versus high (>7) risk groups. The primary endpoint was 30-day and 90-day mortality. We determined the negative predictive value and computed the area under the receiver operating characteristics (AUROC) curves to compare the ability of these scoring tools.
520			_aOBJECTIVE: We evaluated the comparative validity of the PE severity index (PESI) and the prognosis in pulmonary embolism (PREP) scores to predict mortality in acute PE.
520			_aPATIENTS: Consecutive adults (aged >18 years) diagnosed with acute PE.
520			_aRESULTS: The cohort consisted of 302 subjects. Thirty-day mortality was 3.0%, and 4.0% died within 90 days. The PESI and the PREP performed similarly (PESI AUROC: 0.858 [95% confidence interval (CI), 0.773-0.943] vs 0.719 [95% CI, 0.563-0.875] for PREP). Segregating these scores into risk categories did not affect their discriminatory power (AUROC: 0.684 [95% CI, 0.559-0.810] for PESI and 0.790 [95% CI, 0.679-0.903] for PREP). The negative predictive value for death of being classified as low risk by the PESI or PREP was 100% and 99%, respectively.
520			_aSETTING: Washington Hospital Center, Washington, DC.
546			_aEnglish
650			_a*Pulmonary Embolism/di [Diagnosis]
650			_a*Pulmonary Embolism/mo [Mortality]
650			_a*Severity of Illness Index
650			_aAdult
650			_aAged
650			_aCohort Studies
650			_aFemale
650			_aHumans
650			_aMale
650			_aMiddle Aged
650			_aPredictive Value of Tests
650			_aPrognosis
650			_aRetrospective Studies
650			_aRisk Factors
651			_aMedStar Washington Hospital Center
656			_aMedicine/Pulmonary-Critical Care
657			_aComparative Study
657			_aJournal Article
657			_aObservational Study
700			_aChan, Chee Man
700			_aShorr, Andrew F
700			_aWoods, Christian J
790			_aChan CM, Shorr AF, Woods CJ
856			_uhttp://dx.doi.org/10.1002/jhm.932 _zhttp://dx.doi.org/10.1002/jhm.932
942			_cART _dArticle
999			_c1153 _d1153