| 000 | 02606nam a22003857a 4500 | ||
|---|---|---|---|
| 008 | 230815s20232023 xxu||||| |||| 00| 0 eng d | ||
| 022 | _a2226-4787 | ||
| 024 | _a10.3390/pharmacy11040113 [doi] | ||
| 024 | _apharmacy11040113 [pii] | ||
| 024 | _aPMC10366912 [pmc] | ||
| 040 | _aOvid MEDLINE(R) | ||
| 099 | _a37489344 | ||
| 245 | _aEvaluation of Peak Inspiratory Flow Rate in Hospitalized Palliative Care Patients with COPD. | ||
| 251 | _aPharmacy : A Journal Of Pharmacy Education And Practice. 11(4), 2023 Jul 06. | ||
| 252 | _aPharmacy (Basel). 11(4), 2023 Jul 06. | ||
| 253 | _aPharmacy (Basel, Switzerland) | ||
| 260 | _c2023 | ||
| 260 | _fFY2024 | ||
| 260 | _p2023 Jul 06 | ||
| 265 | _sepublish | ||
| 265 | _tPubMed-not-MEDLINE | ||
| 266 | _d2023-08-15 | ||
| 520 | _aDry powder inhalers are an effective yet costly COPD medication-delivery device. Patients must possess a minimum peak inspiratory flow rate (PIFR) for inhaled medication to be properly deposited into the lungs. Hospitalized palliative-care patients with diminished lung function due to advanced COPD may not possess the minimum PIFR (30 L/min) for adequate drug delivery. This study aims to quantify PIFR values for hospitalized palliative-care patients with advanced COPD to evaluate whether these patients meet the minimum PIFR requirements. Hospitalized patients >=18 years old with a palliative-care consultation were eligible if they had a diagnosis of advanced COPD (GOLD C or D). Patients were excluded if they lacked decision-making capacity or had a positive COVID-19 test within the previous 90 days. Three PIFR values were recorded utilizing the In-CheckTM device, with the highest of the three PIFR attempts being utilized for statistical analysis. Eighteen patients were enrolled, and the mean of the highest PIFR readings was 72.5 L/min (+/-29 L/min). Post hoc analysis indicated 99.9% power when comparing the average best PIFR to the minimum PIFR (30 L/min) but only 51.4% power when compared to the optimal PIFR (60 L/min). This study found that palliative-care patients possess the minimum PIFR for DPI drug delivery. | ||
| 546 | _aEnglish | ||
| 650 | _zAutomated | ||
| 651 | _aMedStar Franklin Square Medical Center | ||
| 656 | _aAVP, Palliative Care | ||
| 656 | _aMedStar Health | ||
| 657 | _aJournal Article | ||
| 700 |
_aCook, Heather _bMFSMC |
||
| 700 |
_aWalker, Kathryn A _bMSH |
||
| 790 | _aBorris J, Chae S, Cook H, McPherson ML, Walker KA | ||
| 856 |
_uhttps://dx.doi.org/10.3390/pharmacy11040113 _zhttps://dx.doi.org/10.3390/pharmacy11040113 |
||
| 942 |
_cART _dArticle |
||
| 999 |
_c13071 _d13071 |
||