000 03648nam a22006737a 4500
008 130912s20122012 xxu||||| |||| 00| 0 eng dOvid Technologies
022 _a1476-4954
040 _aOvid MEDLINE(R)
099 _a21955004
245 _aThe impact of pre-pregnancy body mass index on the risk of gestational diabetes.
251 _aJournal of Maternal-Fetal & Neonatal Medicine. 25(1):5-10, 2012 Jan.
252 _aJ Matern Fetal Neonatal Med. 25(1):5-10, 2012 Jan.
253 _aThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
260 _c2012
260 _fFY2012
266 _d2013-09-17
501 _aAvailable online through MWHC library: 2013 to the present
520 _aCONCLUSIONS: GDM is a multifactorial disorder and pre-pregnancy BMI plays an important role in that risk. Modest 130912s in pre-pregnancy BMI may decrease the risk of GDM substantially.
520 _aMETHODS: We performed a case control study using data collected in The Consortium on Safe Labor database. The association between BMI and GDM was evaluated both using BMI weight categories adopted by the National Institute of Health, and separately using BMI as a continuous variable. Multiple logistic regression analyses were used to evaluate the effects of BMI, age, ethnicity, parity, chronic hypertension and antenatal steroid use on the risk of GDM. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to approximate relative risks of GDM. A p value of <0.05 was considered significant.
520 _aOBJECTIVE: To evaluate the effect of pre-pregnancy body mass index (BMI) on the risk of developing gestational diabetes mellitus (GDM) in a large unselected population.
520 _aRESULTS: After controlling for other factors, the risk of GDM increased with an increasing BMI across all weight categories. For each 1 kg/m(2) increase of BMI the OR of developing GDM was 1.08 (95% CI 1.08-1.09) and for each 5 kg/m(2) increase, the OR was 1.48 (95% CI 1.45-1.51).
546 _aEnglish
650 _a*Body Mass Index
650 _a*Diabetes, Gestational/ep [Epidemiology]
650 _a*Preconception Care
650 _aCase-Control Studies
650 _aDiabetes, Gestational/eh [Ethnology]
650 _aEthnic Groups
650 _aFemale
650 _aHumans
650 _aHypertension
650 _aLogistic Models
650 _aNational Institutes of Health (U.S.)
650 _aObesity/co [Complications]
650 _aObesity/di [Diagnosis]
650 _aOdds Ratio
650 _aParity
650 _aPregnancy
650 _aPregnancy Complications
650 _aRisk Factors
650 _aUnited States
651 _aMedStar Health Research Institute
651 _aMedStar Washington Hospital Center
656 _aObstetrics and Gynecology/Maternal-Fetal Medicine
657 _aJournal Article
657 _aResearch Support, N.I.H., Extramural
657 _aResearch Support, Non-U.S. Gov't
700 _aAmini, Dennis
700 _aDriggers, Rita W
700 _aHuang, Chun Chih
700 _aLandy, Helain J
700 _aMiodovnik, Menachem
700 _aSingh, Jasbir
700 _aTimofeev, Julia
700 _aUmans, Jason G
790 _aAmini D, Driggers RW, Huang CC, Landy HJ, Miodovnik M, Singh J, Timofeev J, Umans JG
856 _uhttp://dx.doi.org/10.3109/14767058.2012.626920
_zhttp://dx.doi.org/10.3109/14767058.2012.626920
942 _cART
_dArticle
999 _c1324
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