000			03132nam a22003857a 4500
266			_d2024-01-22
008			240122s20232023xxu||||| |||| 00| 0 eng d
022			_a2078-6891
024			_a10.21037/jgo-23-599 [doi]
024			_ajgo-14-05-2039 [pii]
024			_aPMC10643593 [pmc]
040			_aOvid MEDLINE(R)
099			_a37969839
245			_aHigh albumin-bilirubin grade predicts worse short-term complications in gastric cancer patients with metabolic syndrome: a retrospective study.
251			_aJournal of Gastrointestinal Oncology. 14(5):2039-2047, 2023 Oct 31.
252			_aJ. gastrointest. oncol.. 14(5):2039-2047, 2023 Oct 31.
253			_aJournal of gastrointestinal oncology
260			_c2023
260			_fFY2024
260			_p2023 Oct 31
265			_sppublish
265			_tPublisher
520			_aBackground: Preoperative albumin-bilirubin (ALBI) grade has been proposed and applied in recent years to evaluate the prognosis of liver cancer, but its role in gastric cancer (GC) is still unclear. This research aimed to examine the prognostic value of ALBI grade after gastrectomy among patients with GC complicated with metabolic syndrome (MetS).
520			_aConclusions: The preoperative ALBI grade is important in the prognosis of GC patients with MetS after gastrectomy. GC patients with MetS can lower their incidence of serious complications by adjusting their preoperative ALBI grade. Copyright 2023 Journal of Gastrointestinal Oncology. All rights reserved.
520			_aMethods: There were 628 patients who received radical resection for GC. Laboratory data and short-term results were collected prospectively, and preoperative ALBI grades were calculated from the albumin and bilirubin levels. The appropriate ALBI cutoff value was calculated by receiver operating characteristic (ROC) curve analysis, which we used to put patients into high (>-2.54) and low (<=-2.54) ALBI grade groups. The differences between the short-term complication rates of the two groups were analyzed with the chi-square test.
520			_aResults: Of the included patients, 133 (21.2%) and 495 (78.8%) had high and low ALBI grades, respectively. A high ALBI grade (P=0.001), body mass index (BMI) >=25 kg/m2 (P=0.001), and hypertension (P=0.018) were independent risk factors for postoperative complications. In GC patients with and without MetS, the high ALBI subgroup showed more overall complications than the low ALBI subgroup (P=0.028 and P=0.001). Among GC patients with MetS, those with a high ALBI grade showed a higher incidence of serious complications than those with a low ALBI grade (P=0.001); a similar, nonsignificant trend occurred in non-MetS patients (P=0.153).
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
656			_aMedstar Southern Maryland Hospital Center
657			_aJournal Article
700			_aMadan, Ankit _bMSMC
790			_aLuo X, Chen XD, Chen JL, Wang WB, Madan A, Song HN, Huang DD, Chen XL, Dong QT
856			_uhttps://dx.doi.org/10.21037/jgo-23-599 _zhttps://dx.doi.org/10.21037/jgo-23-599
942			_cART _dArticle
999			_c13848 _d13848