000			01808nam a22002777a 4500
008			240424s20242024 xxu||||| |||| 00| 0 eng d
040			_aOvid MEDLINE(R)
099			_a31613538
245			_aHistology, Parietal Cells.
251			_aStatPearls Publishing. 2024 01
252			_aStatPearls Publishing. 2024 01
260			_c2024
260			_fFY2024
260			_p2024 01
265			_sppublish
266			_d2024-04-24
520			_aUnique to the human body due to its acid-secreting ability, the parietal cell has always been a subject of interest for scientific research. Harbored in the gastric glands of the fundus and body, parietal cells are considered to be dynamic, as they undergo morphological transition during the resting and secretory states. Parietal cells play a pivotal role in gastric homeostasis, as well as in the absorption of vitamin B12 (cobalamin) due to the release of intrinsic factor (IF). Paracrine, endocrine, and neural pathways are involved in the rigorous control of acid secretion by parietal cells. Therefore, they play an important role in gastric pathologies and are considered to be crucial in the pathophysiology of acid reflux disease, different causes of gastritis, pernicious anemia, Helicobacter pylori infection, among others. It is imperative to understand their physiology, structure, and clinical relevance to grasp the importance of the said cells in the gastric environment. Copyright © 2024, StatPearls Publishing LLC.
546			_aEnglish
650			_aIN PROCESS -- NOT YET INDEXED
656			_aMedStar Georgetown University Hospital/MedStar Washington Hospital Center
656			_aPediatrics Residency
657			_aStudy Guide
700			_aVarela, Carlos D. _bMGUH _dMD
790			_aVarela CD, Segura N
942			_cART _dArticle
999			_c14080 _d14080