000			03469nam a22003857a 4500
008			240723s20242024 xxu||||| |||| 00| 0 eng d
022			_a1878-8750
024			_aS1878-8750(24)00602-8 [pii]
040			_aOvid MEDLINE(R)
099			_a38616025
245			_aDepression State Correlates with Functional Recovery Following Elective Lumbar Spine Fusion.
251			_aWorld Neurosurgery. 2024 Apr 12
252			_aWorld Neurosurg. 2024 Apr 12
253			_aWorld neurosurgery
260			_c2024
260			_p2024 Apr 12
265			_saheadofprint
265			_tPublisher
266			_d2024-07-23
520			_aCONCLUSIONS: Our study investigated the relationship between depression and postoperative PROMIS scores and identified situationally depressed patients as having the worst preoperative impairment. Despite this, the situationally depressed cohort had the highest likelihood of achieving MCID PF, suggestive of a bidirectional relationship between lumbar degenerative disease and subclinical, situational depression. These findings may help guide preoperative counseling on expectations, and patient selection. Copyright © 2024. Published by Elsevier Inc.
520			_aMETHODS: Adult patients undergoing elective 1-3 level lumbar fusion were reviewed. Patients with a formal diagnosis of major depression were classified as "clinically depressed" whereas patients with at least "mild" PROMIS Depression scores in the absence of formal depression diagnosis were deemed "situationally depressed." ANOVA testing was used to assess differences within and between groups. Multivariate regression was used to identify features associated with the achievement of MCID.
520			_aOBJECTIVE: To determine how depression state impacts postoperative Patient-Reported Outcomes Measurement Information System (PROMIS) scores and achievement of minimum clinically important difference (MCID) following lumbar fusion. Depression has been shown to negatively impact outcomes following numerous orthopedic surgeries. Situational and major clinical depression can differentially affect postoperative outcomes.
520			_aRESULTS: 200 patients were included. The average age was 65.9 +/- 12.2 years. 75 patients (37.5%) were non-depressed, 66 patients (33.0%) were clinically depressed, and 59 patients (29.5%) were situationally depressed. Situationally depressed patients had worse preoperative PF and PI scores and were more likely to have severe symptoms (P=0.001, P=0.001). All groups improved significantly from preoperative baseline scores. All groups met MCID PF at different rates, with highest proportion of situationally depressed reaching this metric (P = 0.03). Rates of achieving MCID PI were not significantly different between groups (P=0.47). Situational depression was predictive of achieving MCID PF (P=0.002) but not MCID PI.
520			_aSTUDY DESIGN: Retrospective review of single-institution cohort.
546			_aEnglish
650			_zAutomated
650			_aIN PROCESS -- NOT YET INDEXED
651			_aMedStar Washington Hospital Center
656			_aOrthopedic Surgery
657			_aJournal Article
700			_aMesfin, Addisu _bMWHC
790			_aCady-McCrea CI, Shaikh HJF, Mannava S, Stone J, Hassanzadeh H, Mesfin A, Molinari RW, Menga EN, Rubery PT, Puvanesarajah V
856			_uhttps://dx.doi.org/10.1016/j.wneu.2024.04.039 _zhttps://dx.doi.org/10.1016/j.wneu.2024.04.039
942			_cART _dArticle
999			_c14174 _d14174