000 02531nam a22004217a 4500
008 240723s20242024 xxu||||| |||| 00| 0 eng d
022 _a2000-9666
024 _ajchim-14-01-030 [pii]
024 _aPMC10932497 [pmc]
040 _aOvid MEDLINE(R)
099 _a38482098
245 _aPulmonary Clostridium perfringens: Seeding Beyond the Gastrointestinal Tract.
251 _aJournal of Community Hospital Internal Medicine Perspectives. 14(1):30-34, 2024.
252 _aJ Community Hosp Intern Med Perspect. 14(1):30-34, 2024.
253 _aJournal of community hospital internal medicine perspectives
260 _c2024
260 _p2024
260 _fFY2024
265 _sepublish
265 _tPubMed-not-MEDLINE
520 _aClostridia perfringens infection outside the gastrointestinal system is rare. Here, we report on a 75-year-old man with history of end-stage renal disease presenting after a syncopal event with lactic acidosis, leukocytosis, and mild hyper-bilirubinemia. Chest imaging revealed a loculated, left-sided pleural effusion; diagnostic thoracentesis identified Clostridia perfringens, consistent with an empyema. Video-assisted thoracic left lung decortication was performed; tissue culture also speciated Clostridia perfringens. Further imaging revealed concomitant acute cholecystitis, suggesting hematogenous seeding or transdiaphragmatic extension of Clostridia perfringens to pleural space from an abdominal source. The patient was successfully managed with laparoscopic cholecystectomy and discharged on a one-month course of amoxicillin-sulbactam. This case highlights the potential for Clostridia perfringens to produce a pleuropulmonary infection, necessitating timely diagnosis and intervention, to improve patient outcomes. Copyright © 2024 Greater Baltimore Medical Center.
546 _aEnglish
650 _zAutomated
651 _aMedStar Franklin Square Medical Center
651 _aMedStar Union Memorial Hospital
656 _aHospitalist
656 _aInfectious Diseases
656 _aInternal Medicine Residency
656 _aMedicine
657 _aCase Reports
700 _aDelungahawatta, Thilini
_bMUMH
_cInternal Medicine Residency
_dMBBS
700 _aHaas, Christopher
_bMFSMC
700 _aRao, Shiavax J
_bMUMH
700 _aWolff, Marcos
_bMFSMC
790 _aDelungahawatta T, Rao SJ, Wolff M, Haas CJ
856 _uhttps://dx.doi.org/10.55729/2000-9666.1274
_zhttps://dx.doi.org/10.55729/2000-9666.1274
942 _cART
_dArticle
999 _c14274
_d14274