000 02933nam a22003617a 4500
008 240723s20232023 xxu||||| |||| 00| 0 eng d
022 _a2772-5723
024 _aNIHMS1858900 [mid]
024 _aPMC10022591 [pmc]
040 _aOvid MEDLINE(R)
099 _a36938381
245 _aTime to Publication for Randomized Clinical Trials Presented as Abstracts at Three Gastroenterology and Hepatology Conferences in 2017.
251 _aGastro Hep Advances. 2(3):370-379, 2023 Mar.
252 _aGastro Hep Adv. 2(3):370-379, 2023 Mar.
253 _aGastro hep advances
260 _c2023
260 _p2023 Mar
260 _fFY2023
265 _sppublish
265 _tPubMed-not-MEDLINE
520 _aBackground & Aims: Results of randomized clinical trials are often first presented as conference abstracts, but these abstracts may be difficult to find, and trial results included in the abstract may not be followed by subsequent journal publications. In a review of abstracts submitted to eight major medical and surgical conferences in 2017, we identified 237 abstracts reporting primary results of randomized clinical trials accepted for presentation at three major gastroenterology and hepatology conferences. The aims of this new analysis were to determine the publication rate for these abstracts and the proportion of publications that included trial registration numbers in the publication abstract.
520 _aConclusions: Clinical trial results could be more accessible if all trials were registered, authors included registration numbers in both conference and journal abstracts, and journal editors required the inclusion of registration numbers in publication abstracts for registered clinical trials.
520 _aMethods: Clinical trial registries, PubMed, Europe PMC, and Google Scholar were searched through November 1, 2021, for publications reporting trial results for the selected abstracts. Publications were reviewed to determine if they included a trial registration number and if the registration number was in the abstract.
520 _aResults: Publications were found for 157 abstracts (66%) within four years of the conference. Publications were found more frequently for the 194 abstracts reporting results of registered trials (144, 74%) than for the 43 abstracts reporting unregistered trials (13, 30%), but only 67% of these 144 publications included the registration number in the publication abstract. Ten unpublished trials had summary results posted on ClinicalTrials.gov.
546 _aEnglish
650 _zAutomated
651 _aMedStar Good Samaritan Hospital
657 _aJournal Article
700 _aBasu, Dev
_bMGSH
790 _aWright EC, Kapuria D, Ben-Yakov G, Sharma D, Basu D, Cho MH, Abijo T, Wilkins KJ
856 _uhttps://dx.doi.org/10.1016/j.gastha.2022.12.003
_zhttps://dx.doi.org/10.1016/j.gastha.2022.12.003
942 _cART
_dArticle
999 _c14284
_d14284